Analytical Data
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Gene name
C10orf62
- Application
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Alternative Names
C10orf62Uncharacterized Protein C10orf62
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5T681
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Expression Region
1-223aa
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AA Sequence
MLWVQRKRRRKETSECPSDKDKSPESHKAKNESWIKSHFSRLSEEKLALDNNASASGNATQTESGSEEVSSTVHIETFTTRHGEVGSALHRESFTSRQKTSGPSVIQEIHQESGKAPSTDDATWAAVAACTKEIDTQGRHLAHSMLQRAIAYQHSGHLESKDINQEELRALEEVEMKLQKNFLTQRENTIAGANHTHTFYGHSHHSHHGHPSHQSHSLPNRRH
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Molecular Weight
51.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C10orf62, also known as "chromosome 10 open reading frame 62," is a gene located on chromosome 10 that has garnered attention due to its potential role in various biological processes and diseases. Recent studies have implicated C10orf62 in neurodegenerative disorders, particularly in the context of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The protein encoded by this gene is believed to influence cellular functions, including stress responses and neuroinflammation, underscoring its significance in neuronal health. Research involving the recombinant expression of C10orf62 protein aims to elucidate its functional properties, interactions, and potential as a biomarker for disease progression. By generating and analyzing this recombinant protein, scientists can investigate its biochemical characteristics, assess its role in cellular pathways, and examine its impact on neuronal survival or degeneration. Furthermore, understanding the mechanisms through which C10orf62 operates may reveal novel therapeutic targets for ALS and FTD, driving forward the search for effective treatments for these debilitating conditions. As such, the study of C10orf62 is not only pivotal for comprehending underlying neurodegenerative mechanisms but also holds promise for advancing personalized medicine approaches in neurological research.
