Analytical Data
-
Gene name
BPIL3
- Application
-
Alternative Names
Bpifb6; Bpil3; Gm119BPI fold-containing family B member 6; Bactericidal/permeability-increasing Protein-like 3
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q8NFQ5
-
Expression Region
1-453aa
-
AA Sequence
MLRILCLALCSLLTGTRADPGALLRLGMDIMNQVQSAMDESHILEKMAAEAGKKQPGMKPIKGITNLKVKDVQLPVITLNFVPGVGIFQCVSTGMTVTGKSFMGGNMEIIVALNITATNRLLRDEETGLPVFKSEGCEVILVNVKTNLPSNMLPKMVNKFLDSTLHKVLPGLMCPAIDAVLVYVNRKWTNLSDPMPVGQMGTVKYVLMSAPATTASYIQLDFSPVVQQQKGKTIKLADAGEALTFPEGYAKGSSQLLLPATFLSAELALLQKSFHVNIQDTMIGELPPQTTKTLARFIPEVAVAYPKSKPLTTQIKIKKPPKVTMKTGKSLLHLHSTLEMFAARWRSKAPMSLFLLEVHFNLKVQYSVHENQLQMATSLDRLLSLSRKSSSIGNFNERELTGFITSYLEEAYIPVVNDVLQVGLPLPDFLAMNYNLAELDIVENALMLDLKLG
-
Molecular Weight
76.78 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BPIL3, a member of the BPI (bactericidal/permeability-increasing) protein family, has garnered attention due to its potential role in the immune response and its antimicrobial properties. These proteins are known for their ability to bind and neutralize lipopolysaccharides from Gram-negative bacteria, thereby contributing to host defense mechanisms. The understanding of BPIL3's structure, function, and interactions at the molecular level is critical for comprehending its role in immunological processes. Recent studies suggest that BPIL3 may influence inflammation and antimicrobial activity, highlighting its potential therapeutic applications. Furthermore, the recombinant expression of BPIL3 provides an opportunity to study its properties in vitro, paving the way for developing novel strategies to enhance immune responses or create new antimicrobial agents. Research focusing on the biochemical characterization and functional analysis of BPIL3 is essential for elucidating its role in health and disease, with implications for treating infections and inflammatory conditions.
