Analytical Data
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Gene name
HAPLN3
- Application
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Alternative Names
HAPLN3；EXLD1；Hyaluronan and proteoglycan link Protein 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96S86
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Expression Region
18-360aa
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AA Sequence
LPFYNGFYYSNSANDQNLGNGHGKDLLNGVKLVVETPEETLFTYQGASVILPCRYRYEPALVSPRRVRVKWWKLSENGAPEKDVLVAIGLRHRSFGDYQGRVHLRQDKEHDVSLEIQDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQSPNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQYPIMLPRQPCGGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAREACQEDDATIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSFGFPDPQSRLYGVYCYRQH
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Molecular Weight
42.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HAPLN3 (Hyaluronan Binding Protein Link Protein 3) is a member of the link protein family, which plays a crucial role in the assembly and stabilization of the extracellular matrix (ECM), particularly in relation to hyaluronan, a key component of connective tissues. Research into HAPLN3 has gained traction due to its potential implications in various biological processes, including tissue development, repair, and pathologies such as cancer, arthritis, and cardiovascular diseases. Elevated levels of HAPLN3 have been associated with tumor progression and metastasis, leading to an interest in its functional roles in cell adhesion, migration, and proliferation. The recombinant expression of HAPLN3 enables detailed studies of its biochemical properties, interactions with hyaluronan, and its influences on cellular behavior in controlled environments. By generating and characterizing HAPLN3 recombinant proteins, researchers aim to elucidate its mechanisms of action and explore its potential as a therapeutic target or biomarker in disease contexts. Overall, the investigation of HAPLN3 is significant for understanding ECM dynamics and the intricate relationships between cellular activities and the surrounding microenvironment.
