Cat: PA2000-1700

Recombinant Human HAPLN2 Protein,His

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Analytical Data

  • Gene name

    HAPLN2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    HAPLN2;BRAL1;Hyaluronan and proteoglycan link Protein 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9GZV7

  • Expression Region

    27-340aa

  • AA Sequence

    DPASHPGPHYLLPPIHEVIHSHRGATATLPCVLGTTPPSYKVRWSKVEPGELRETLILITNGLHARGYGPLGGRARMRRGHRLDASLVIAGVRLEDEGRYRCELINGIEDESVALTLSLEGVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGRGRPGIRSYGPRDRMRDRYDAFCFTSALAGQVFFVPGRLTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSFGFPRPQQAAYGTYCYAEN

  • Molecular Weight

    40.8 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

HAPLN2 (Hyaluronan-Interacting Protein 2) is a member of the HAPLN family, which plays a critical role in the extracellular matrix (ECM) organization and maintenance. The protein is known for its ability to interact with hyaluronic acid, a major component of the ECM, thereby influencing tissue structure and function. Studies have indicated that HAPLN2 is involved in various physiological processes, including cell adhesion, migration, and proliferation. Aberrant expression of HAPLN2 has been associated with several pathological conditions, including cancer progression and various inflammatory diseases. Given its significance in ECM dynamics and potential implications in disease, HAPLN2 has become an important target for research aimed at understanding ECM-related disorders and developing therapeutic strategies. Recombinant HAPLN2 protein has been produced for further studies, facilitating detailed investigations into its biological functions, interactions, and role in disease mechanisms. This research is not only pivotal for advancing our understanding of HAPLN2 in a physiological context but also for exploring its potential as a biomarker or therapeutic target in various diseases.

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