Analytical Data
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基因名
BCL2L13
- Application
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别名
BCL2L13; MIL1; CD003; Bcl-2-like Protein 13; Bcl2-L-13; Bcl-rambo; Protein Mil1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BXK5
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表达区间
1-485aa
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氨基酸序列
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTRESDTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK
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分子量
79.09 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BCL2L13 is a member of the BCL-2 family of proteins, which play crucial roles in regulating apoptosis and cellular survival. Recent studies have uncovered that BCL2L13 possesses a unique function beyond its apoptotic regulatory capabilities, specifically its involvement in mitochondrial dynamics and cellular responses to stress. The gene encoding BCL2L13 has been linked to various cellular processes, including oxidative stress response and inflammation, indicating its potential impact on diseases such as neurodegenerative disorders and cancer. The functional characterization of BCL2L13 is of significant interest to researchers aiming to understand its mechanistic roles in cell survival and death. A key focus has been on the production and investigation of recombinant BCL2L13 proteins, which facilitate the study of its structure-function relationships and interactions with other mitochondrial proteins. Such studies could reveal novel insights into the molecular mechanisms underlying mitochondrial dysfunction and apoptosis, potentially leading to the development of therapeutic strategies targeting BCL2L13-related pathways in disease contexts. The exploration of BCL2L13 as a therapeutic target further emphasizes the relevance of this protein in maintaining mitochondrial integrity and cellular homeostasis, underscoring the importance of ongoing research in this area.
