Analytical Data
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基因名
FIS1
- Application
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别名
FIS1;TTC11;Mitochondrial fission 1 Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y3D6
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表达区间
1-122aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG
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分子量
16 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FIS1, or mitochondrial fission 1, is a vital protein that plays a critical role in mitochondrial dynamics, especially in the processes of mitochondrial fission and fusion. Mitochondria, known as the powerhouses of the cell, are dynamic organelles that undergo continuous changes in morphology and distribution to adapt to cellular energy demands and stress conditions. The FIS1 protein is integral to the fission process, facilitating the division of mitochondria, which is essential for maintaining mitochondrial function, cellular health, and energy metabolism. Dysfunction in mitochondrial dynamics is associated with various diseases, including neurodegenerative disorders, metabolic syndromes, and other age-related conditions. Therefore, understanding the structural and functional characteristics of FIS1 is crucial for elucidating its role in mitochondrial biology. Recent research has focused on characterizing FIS1 and understanding its interactions with other proteins involved in mitochondrial dynamics, providing insights into how alterations in FIS1 expression or function may contribute to mitochondrial dysfunction and disease pathology. The exploration of FIS1 as a potential therapeutic target or biomarker for diseases associated with mitochondrial dysfunction is also gaining interest, highlighting its significance in both basic and clinical research.












