Analytical Data
-
Gene name
BAPX1
- Application
-
Alternative Names
Nkx3-2; Bapx1; Nkx-3.2; Nkx3bHomeobox Protein Nkx-3.2; Bagpipe homeobox Protein homolog 1; Homeobox Protein NK-3 homolog B
-
Species
Mouse
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P97503
-
Expression Region
1-333aa
-
AA Sequence
MAVRGSGTLT PFSIQAILNK KEERGGLATP EGRPAPGGTE VAVTAAPAVC CWRIFGETEA GALGGAEDSL LASPARTRTA VGQSAESPGG WDSDSALSEE NEGRRRCADV PGASGTGRAR VTLGLDQPGC ELHAAKDLEE EAPVRSDSEM SASVSGDHSP RGEDDSVSPG GARVPGLRGA AGSGASGGQA GGVEEEEEPA APKPRKKRSR AAFSHAQVFE LERRFNHQRY LSGPERADLA ASLKLTETQV KIWFQNRRYK TKRRQMAADL LASAPAAKKV AVKVLVRDDQ RQYLPGEVLR PPSLLPLQPS YYYPYYCLPG WALSTCAAAA GTQ
-
Molecular Weight
35 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BAPX1 (Bone morphogenetic protein-2/4-responsive transcription factor) is a member of the NKX family of homeobox genes that plays a crucial role in the development and patterning of various tissues, particularly in the heart and skeletal system. Its expression is tightly regulated during embryonic development, influencing processes such as organogenesis and the differentiation of mesodermal progenitor cells. Dysregulation or mutations in BAPX1 have been linked to various congenital anomalies, reinforcing its importance in developmental biology. Recent studies have focused on the production and characterization of recombinant BAPX1 protein to explore its biochemical properties and functional roles in cellular signaling pathways. Understanding the structure-function relationship of BAPX1 will provide insights into its mechanism of action and potential implications in regenerative medicine and targeted therapies for malformations resulting from its dysfunction. The availability of recombinant BAPX1 opens new avenues for research into its interactions with other signaling molecules and transcription factors, thereby contributing to a deeper understanding of heart and skeleton development, as well as potential therapeutic strategies for related diseases.
