Analytical Data
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基因名
PIGV
- Application
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别名
GPI mannosyltransferase 2; GPI mannosyltransferase II; GPI MT II; GPI-MT-II; Phosphatidylinositol glycan biosynthesis class V protein; Phosphatidylinositol-glycan biosynthesis class V protein; PIG-V; Pigv; PIGV_HUMAN
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NUD9
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表达区间
1-493 aa
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氨基酸序列
MWPQDPSRKEVLRFAVSCRILTLMLQALFNAIIPDHHAEAFSPPRLAPSGFVDQLVEGLLGGLSHWDAEHFLFIAEHGYLYEHNFAFFPGFPLALLVGTELLRPLRGLLSLRSCLLISVASLNFLFFMLAAVALHDLGCLVLHCPHQSFYAALLFCLSPANVFLAAGYSEALFALLTFSAMGQLERGRVWTSVLLFAFATGVRSNGLVSVGFLMHSQCQGFFSSLTMLNPLRQLFKLMASLFLSVFTLGLPFALFQYYAYTQFCLPGSARPIPEPLVQLAVDKGYRIAEGNEPPWCFWDVPLIYSYIQDVYWNVGFLKYYELKQVPNFLLAAPVAILVAWATWTYVTTHPWLCLTLGLQRSKNNKTLEKPDLGFLSPQVFVYVVHAAVLLLFGGLCMHVQVLTRFLGSSTPIMYWFPAHLLQDQEPLLRSLKTVPWKPLAEDSPPGQKVPRNPIMGLLYHWKTCSPVTRYILGYFLTYWLLGLLLHCNFLPWT
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分子量
82.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PIGV (phosphatidylinositol glycan anchor biosynthesis class V) is an essential gene involved in the glycosylphosphatidylinositol (GPI) anchor biosynthetic pathway, which plays a critical role in cell membrane anchoring of various proteins. Abnormalities in PIGV are linked to inherited human disorders, notably GPI-anchor deficiency syndrome, which can lead to a range of clinical manifestations including immunodeficiency, neurological issues, and developmental abnormalities. The research on recombinant PIGV protein aims to deepen our understanding of its structure-function relationships and its role in GPI-anchor biosynthesis. By producing and characterizing recombinant PIGV, researchers hope to elucidate the molecular mechanisms underlying GPI anchor formation and to explore potential therapeutic avenues for diseases related to PIGV mutations. Insights gained from this research could pave the way for novel treatments as well as improve our understanding of glycosylation processes and their implications in health and disease. As such, the study of recombinant PIGV is not only a vital endeavor in the field of glycobiology but also holds promise for translating basic research findings into clinical applications.
