Analytical Data
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Gene name
B4GALT7
- Application
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Alternative Names
B4GALT7; XGALT1; UNQ748/PRO1478Beta-1.4-galactosyltransferase 7
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UBV7
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Expression Region
1-327aa
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AA Sequence
MFPSRRKAAQLPWEDGRSGLLSGGLPRKCSVFHLFVACLSLGFFSLLWLQLSCSGDVARAVRGQGQETSGPPRACPPEPPPEHWEEDASWGPHRLAVLVPFRERFEELLVFVPHMRRFLSRKKIRHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFPEAGPFHVASPELHPLYHYKTYVGGILLLSKQHYRLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPSGITTGYKTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYHVASRTALSVGGAPCTVLNIMLDCDKTATPWCTFS
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Molecular Weight
37.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
B4GALT7, a member of the β1,4-galactosyltransferase family, plays a crucial role in glycosylation processes, particularly in the synthesis of glycosaminoglycans (GAGs) such as heparan sulfate, which are vital for various biological functions including cell signaling, development, and tissue homeostasis. The enzyme catalyzes the addition of galactose residues to acceptor substrates, influencing the structural diversity and functions of glycan chains. Dysregulation of B4GALT7 has been implicated in several pathological conditions, including developmental disorders and cancer, making it a significant focus of research in glycobiology. Moreover, understanding the structure and function of B4GALT7 can provide insights into its enzymatic mechanisms, potential interactions with other biomolecules, and its role in disease progression. Recent advances in biotechnology allow for the recombinant production of B4GALT7, enabling detailed studies on its enzymatic activity, substrate specificity, and the effects of genetic mutations. Such studies are essential for developing therapeutic strategies targeting glycosylation pathways, highlighting the importance of B4GALT7 in both basic and applied sciences.
