Analytical Data
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Gene name
ZFAND5
- Application
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Alternative Names
ZFAND5；ZA20D2；AN1-type zinc finger Protein 5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O76080
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Expression Region
1-213aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAQETNQ TPGPMLCSTG CGFYGNPRTN GMCSVCYKEH LQRQQNSGRM SPMGTASGSN SPTSDSASVQ RADTSLNNCE GAAGSTSEKS RNVPVAALPV TQQMTEMSIS REDKITTPKT EVSEPVVTQP SPSVSQPSTS QSEEKAPELP KPKKNRCFMCRKKVGLTGFD CRCGNLFCGL HRYSDKHNCP YDYKAEAAAK IRKENPVVVA EKIQRI
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Molecular Weight
26 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZFAND5, a member of the ZFAND family of proteins, has emerged as a significant focus in the field of cellular biology and immunology. Its unique structure, characterized by zinc finger domains, suggests a role in manipulating protein interactions and modulating various cellular processes. Research has indicated that ZFAND5 is implicated in the regulation of immune responses, particularly in the context of inflammation and pathogen recognition. Given the rising interest in understanding the molecular mechanisms behind autoimmune diseases and chronic inflammatory conditions, ZFAND5 has garnered attention for its potential as a therapeutic target. Recent studies have explored its interactions with key signaling pathways, including the NF-κB and MAPK pathways, which are crucial for the regulation of inflammatory responses. Additionally, ZFAND5's expression patterns in different tissues and its involvement in various cellular processes underscore its significance as a multifunctional protein. Understanding the biological roles of ZFAND5 could pave the way for novel therapeutic strategies aimed at modulating immune responses and addressing disorders associated with dysregulated inflammation. As research progresses, elucidating the precise mechanisms through which ZFAND5 exerts its effects will be crucial for harnessing its potential in clinical applications.
