Analytical Data
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基因名
B3GNT6
- Application
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别名
B3GNT6Acetylgalactosaminyl-O-glycosyl-glycoProtein beta-1.3-N-acetylglucosaminyltransferase
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6ZMB0
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表达区间
1-384aa
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氨基酸序列
MAFPCRRSLTAKTLACLLVGVSFLALQQWFLQAPRSPREERSPQEETPEGPTDAPAADEPPSELVPGPPCVANASANATADFEQLPARIQDFLRYRHCRHFPLLWDAPAKCAGGRGVFLLLAVKSAPEHYERRELIRRTWGQERSYGGRPVRRLFLLGTPGPEDEARAERLAELVALEAREHGDVLQWAFADTFLNLTLKHLHLLDWLAARCPHARFLLSGDDDVFVHTANVVRFLQAQPPGRHLFSGQLMEGSVPIRDSWSKYFVPPQLFPGSAYPVYCSGGGFLLSGPTARALRAAARHTPLFPIDDAYMGMCLERAGLAPSGHEGIRPFGVQLPGAQQSSFDPCMYRELLLVHRFAPYEMLLMWKALHSPALSCDRGHRVS
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分子量
69.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
B3GNT6, or beta-1,3-N-acetylglucosaminyltransferase 6, is an enzyme implicated in the synthesis of carbohydrate structures known as glycosaminoglycans, which play a crucial role in numerous biological processes, including cell signaling, adhesion, and the maintenance of extracellular matrix integrity. Recent studies have highlighted the significance of B3GNT6 in various physiological and pathological contexts, such as cancer progression and metastasis, due to its involvement in altering glycan structures on cell surfaces. Understanding the enzymatic activity of B3GNT6 and the resulting glycosylation patterns is essential for elucidating its functional roles in health and disease. Additionally, given the potential of glycan modifications in influencing therapeutic responses, B3GNT6 presents a promising target for drug development and biomarker discovery. Researchers are now focused on the recombinant expression of B3GNT6 to facilitate in-depth studies of its biochemical properties, substrate specificity, and interactions with other molecules, paving the way for novel therapeutic approaches that leverage the modulation of glycosylation pathways.
