Cat: PAX2000-10286

Recombinant Human PHF23 Protein,His

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Analytical Data

  • Gene name

    PHF23

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    410141M05Rik; FLJ16355; FLJ22884; hJUNE 1b ; JUNE-1; MGC2941; P23-172M21.13-002; PDH containing protein JUNE 1; PDH-containing protein JUNE-1; PHD finger protein 23; PHD finger protein 23a ; PHF23; PHF23_HUMAN; RP23-172M21.13

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BUL5

  • Expression Region

    1-403 aa

  • AA Sequence

    MLEAMAEPSP EDPPPTLKPE TQPPEKRRRT IEDFNKFCSF VLAYAGYIPP SKEESDWPAS GSSSPLRGES AADSDGWDSA PSDLRTIQTF VKKAKSSKRR AAQAGPTQPG PPRSTFSRLQ APDSATLLEK MKLKDSLFDL DGPKVASPLS PTSLTHTSRP PAALTPVPLS QGDLSHPPRK KDRKNRKLGP GAGAGFGVLR RPRPTPGDGE KRSRIKKSKK RKLKKAERGD RLPPPGPPQA PPSDTDSEEE EEEEEEEEEE EMATVVGGEA PVPVLPTPPE APRPPATVHP EGVPPADSES KEVGSTETSQ DGDASSSEGE MRVMDEDIMV ESGDDSWDLI TCYCRKPFAG RPMIECSLCG TWIHLSCAKI KKTNVPDFFY CQKCKELRPE ARRLGGPPKS GEP

  • Molecular Weight

    43.8 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

PHF23, or PHD finger protein 23, is a member of the PHD finger family of proteins, which play crucial roles in chromatin remodeling and gene regulation. Research into PHF23 has gained attention due to its involvement in various biological processes, including cell differentiation and response to cellular stress. Abnormal expression or mutations in PHF23 have been implicated in several diseases, including cancers and neurodegenerative disorders. The protein contains functional domains that allow it to interact with histones and transcription factors, suggesting its role as a regulatory protein in epigenetic modifications. Recent studies have focused on the structural characterization of recombinant PHF23 proteins to elucidate their functional mechanisms and interactions within the cellular environment. This recombinant protein research aims to provide insights into the biological functions of PHF23, offering potential therapeutic targets for diseases associated with its dysregulation. Understanding the precise role of PHF23 in cellular processes can contribute to the development of novel strategies for disease intervention and provide a clearer picture of how epigenetic regulation influences health and disease.

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