Analytical Data
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基因名
PHACTR3
- Application
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别名
PHACTR3; C20orf101; SCAPIN1; Phosphatase and actin regulator 3; Scaffold-associated PP1-inhibiting protein; Scapinin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96KR7
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表达区间
1-559 aa
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氨基酸序列
MAASEDGSGC LVSRGRSQSD PSVLTDSSAT SSADAGENPD EMDQTPPARP EYLVSGIRTP PVRRNSKLAT LGRIFKPWKW RKKKNEKLKQ TTSALEKKMA GRQGREELIK KGLLEMMEQD AESKTCNPDG GPRSVQSEPP TPKSETLTSE DAQPGSPLAT GTDQVSLDKP LSSAAHLDDA AKMPSASSGE EADAGSLLPT TNELSQALAG ADSLDSPPRP LERSVGQLPS PPLLPTPPPK ASSKTTKNVT GQATLFQASS MKSADPSLRG QLSTPTGSPH LTTVHRPLPP SRVIEELHRA LATKHRQDSF QGRESKGSPK KRLDVRLSRT SSVERGKERE EAWSFDGALE NKRTAAKESE ENKENLIINS ELKDDLLLYQ DEEALNDSII SGTLPRKCKK ELLAVKLRNR PSKQELEDRN IFPRRTDEER QEIRQQIEMK LSKRLSQRPA VEELERRNIL KQRNDQTEQE ERREIKQRLT RKLNQRPTVD ELRDRKILIR FSDYVEVAKA QDYDRRADKP WTRLSAADKA AIRKELNEYK SNEMEVHASS KHLTRFHRP
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分子量
62.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PHACTR3 (phosphatase and actin regulator 3) is a protein that plays a significant role in the regulation of various cellular processes, including cytoskeletal dynamics, cell migration, and signal transduction. Emerging research has highlighted its involvement in cardiovascular development and disease, as well as its potential implications in neurological disorders. The gene encoding PHACTR3 is known to be associated with several key pathways, including those linked to growth factor signaling, which further emphasizes its importance in cellular functions. Additionally, aberrations in PHACTR3 expression levels have been linked to various pathological conditions, shedding light on its potential as a therapeutic target. Recent studies have focused on the structural characteristics and functional mechanisms of PHACTR3, particularly concerning its interactions with actin and phosphatases, thereby advancing our understanding of its role in cellular architecture and function. The exploration of PHACTR3 as a recombinant protein is crucial for elucidating these interactions and for developing potential applications in regenerative medicine and targeted therapies, as it could provide insights into how manipulating this protein may lead to novel treatments for diseases characterized by dysregulated cell behavior.
