Analytical Data
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Gene name
PHACTR3
- Application
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Alternative Names
PHACTR3; C20orf101; SCAPIN1; Phosphatase and actin regulator 3; Scaffold-associated PP1-inhibiting protein; Scapinin
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96KR7
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Expression Region
1-559 aa
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AA Sequence
MAASEDGSGC LVSRGRSQSD PSVLTDSSAT SSADAGENPD EMDQTPPARP EYLVSGIRTP PVRRNSKLAT LGRIFKPWKW RKKKNEKLKQ TTSALEKKMA GRQGREELIK KGLLEMMEQD AESKTCNPDG GPRSVQSEPP TPKSETLTSE DAQPGSPLAT GTDQVSLDKP LSSAAHLDDA AKMPSASSGE EADAGSLLPT TNELSQALAG ADSLDSPPRP LERSVGQLPS PPLLPTPPPK ASSKTTKNVT GQATLFQASS MKSADPSLRG QLSTPTGSPH LTTVHRPLPP SRVIEELHRA LATKHRQDSF QGRESKGSPK KRLDVRLSRT SSVERGKERE EAWSFDGALE NKRTAAKESE ENKENLIINS ELKDDLLLYQ DEEALNDSII SGTLPRKCKK ELLAVKLRNR PSKQELEDRN IFPRRTDEER QEIRQQIEMK LSKRLSQRPA VEELERRNIL KQRNDQTEQE ERREIKQRLT RKLNQRPTVD ELRDRKILIR FSDYVEVAKA QDYDRRADKP WTRLSAADKA AIRKELNEYK SNEMEVHASS KHLTRFHRP
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Molecular Weight
62.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PHACTR3 (phosphatase and actin regulator 3) is a protein that plays a significant role in the regulation of various cellular processes, including cytoskeletal dynamics, cell migration, and signal transduction. Emerging research has highlighted its involvement in cardiovascular development and disease, as well as its potential implications in neurological disorders. The gene encoding PHACTR3 is known to be associated with several key pathways, including those linked to growth factor signaling, which further emphasizes its importance in cellular functions. Additionally, aberrations in PHACTR3 expression levels have been linked to various pathological conditions, shedding light on its potential as a therapeutic target. Recent studies have focused on the structural characteristics and functional mechanisms of PHACTR3, particularly concerning its interactions with actin and phosphatases, thereby advancing our understanding of its role in cellular architecture and function. The exploration of PHACTR3 as a recombinant protein is crucial for elucidating these interactions and for developing potential applications in regenerative medicine and targeted therapies, as it could provide insights into how manipulating this protein may lead to novel treatments for diseases characterized by dysregulated cell behavior.
