Analytical Data
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Gene name
PHACS
- Application
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Alternative Names
1 aminocyclopropane 1 carboxylate synthase; 1 aminocyclopropane 1 carboxylate synthase homolog (Arabidopsis)(non-functional); 1 aminocyclopropane 1 carboxylate synthase homolog; 1-aminocyclopropane-1-carboxylate synthase-like protein 1; 1A1L1_HUMAN; ACC synthase; ACC synthase like protein 1; ACC synthase-like protein 1; Accs; ACS; PHACS; Putative 1 aminocyclopropane 1 carboxylate synthase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96QU6
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Expression Region
1-501 aa
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AA Sequence
MFTLPQKDFR APTTCLGPTC MQDLGSSHGE DLEGECSRKL DQKLPELRGV GDPAMISSDT SYLSSRGRMI KWFWDSAEEG YRTYHMDEYD EDKNPSGIIN LGTSENKLCF DLLSWRLSQR DMQRVEPSLL QYADWRGHLF LREEVAKFLS FYCKSPVPLR PENVVVLNGG ASLFSALATV LCEAGEAFLI PTPYYGAITQ HVCLYGNIRL AYVYLDSEVT GLDTRPFQLT VEKLEMALRE AHSEGVKVKG LILISPQNPL GDVYSPEELQ EYLVFAKRHR LHVIVDEVYM LSVFEKSVGY RSVLSLERLP DPQRTHVMWA TSKDFGMSGL RFGTLYTENQ DVATAVASLC RYHGLSGLVQ YQMAQLLRDR DWINQVYLPE NHARLKAAHT YVSEELRALG IPFLSRGAGF FIWVDLRKYL PKGTFEEEML LWRRFLDNKV LLSFGKAFEC KEPGWFRFVF SDQVHRLCLG MQRVQQVLAG KSQVAEDPRP SQSQEPSDQR R
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Molecular Weight
57.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PHACS (PH domain-containing protein with actin-capping and SH3 domains) is a protein known for its critical role in the regulation of actin dynamics and cell signaling pathways. Research into PHACS has gained traction due to its involvement in various cellular processes, including cytoskeleton organization, cell migration, and intracellular signaling cascades. Abnormalities in PHACS function have been implicated in several diseases, including cancer and autoimmune disorders, making it a significant target for therapeutic intervention. Furthermore, the study of PHACS recombinant proteins allows for a deeper understanding of its structure-function relationship, enabling researchers to elucidate the molecular mechanisms underlying its activity. By employing techniques such as gene cloning, protein expression in systems like E. coli, and purification methods, scientists aim to produce functional PHACS proteins for biophysical characterization and functional assays. These investigations can reveal how PHACS interacts with other cellular components, contributing to the overall understanding of its biological roles and potential applications in medicine. The increasing interest in PHACS underscores the importance of this protein in both basic research and the development of novel therapeutic strategies.
