Analytical Data
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Gene name
PGM2L1
- Application
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Alternative Names
PMMLP;Phosphoglucomutase-2-like 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6PCE3
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Expression Region
1-622 aa
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AA Sequence
MAENTEGDLNSNLLHAPYHTGDPQLDTAIGQWLRWDKNPKTKEQIENLLRNGMNKELRDRLCCRMTFGTAGLRSAMGAGFCYINDLTVIQSTQGMYKYLERCFSDFKQRGFVVGYDTRGQVTSSCSSQRLAKLTAAVLLAKDVPVYLFSRYVPTPFVPYAVQKLKAVAGVMITASHNRKEDNGYKVYWETGAQITSPHDKEILKCIEECVEPWNGSWNDNLVDTSPLKRDPLQDICRRYMEDLKKICFYRELNSKTTLKFVHTSFHGVGHDYVQLAFKVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVLELSLRLAEKENARVVLATDPDADRLAAAELQENGCWKVFTGNELAALFGWWMFDCWKKNKSRNADVKNVYMLATTVSSKILKAIALKEGFHFEETLPGFKWIGSRIIDLLENGKEVLFAFEESIGFLCGTSVLDKDGVSAAVVVAEMASYLETMNITLKQQLVKVYEKYGYHISKTSYFLCYEPPTIKSIFERLRNFDSPKEYPKFCGTFAILHVRDVTTGYDSSQPNKKSVLPVSKNSQMITFTFQNGCVATLRTSGTEPKIKYYAEMCASPDQSDTALLEEELKKLIDALIENFLQPSKNGLIWRSV
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Molecular Weight
75.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PGM2L1, a member of the phosphoglucomutase family, plays a crucial role in carbohydrate metabolism by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. Understanding the function and regulation of PGM2L1 is pivotal, as it is implicated in various metabolic pathways and may influence cellular energy balance. Research has shown that alterations in PGM2L1 expression and activity can be linked to metabolic disorders and certain diseases, making it a significant target for therapeutic interventions. The recombinant production of PGM2L1 enables detailed studies of its enzymatic properties, structure, and interactions with other metabolic enzymes. Moreover, investigating the effects of PGM2L1 on cellular processes can provide insights into the broader implications of glucose metabolism in health and disease. Recent advances in recombinant DNA technology have facilitated the expression of PGM2L1 in model systems, allowing for the development of assays to evaluate its biochemical activity and regulatory mechanisms. Consequently, studying PGM2L1 not only enhances our understanding of fundamental metabolic processes but also holds potential for identifying biomarkers and therapeutic targets in metabolic diseases.
