Analytical Data
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Gene name
VTA1
- Application
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Alternative Names
VTA1；C6orf55；Vacuolar Protein sorting-associated Protein VTA1 homolog
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NP79
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Expression Region
2-307aa
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AA Sequence
AALAPLPPL PAQFKSIQHH LRTAQEHDKR DPVVAYYCRL YAMQTGMKID SKTPECRKFL SKLMDQLEAL KKQLGDNEAI TQEIVGCAHL ENYALKMFLY ADNEDRAGRF HKNMIKSFYT ASLLIDVITV FGELTDENVK HRKYARWKAT YIHNCLKNGE TPQAGPVGIE EDNDIEENED AGAASLPTQP TQPSSSSTYD PSNMPSGNYT GIQIPPGAHA PANTPAEVPH STGVASNTIQ PTPQTIPAID PALFNTISQG DVRLTPEDFA RAQKYCKYAG SALQYEDVST AVQNLQKALK LLTTGRE
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
VTA1 (Vps28-Interacting Tail-anchored Protein 1) is a novel protein that has garnered attention due to its role in cellular processes related to the endosomal and lysosomal pathways. It is involved in the sorting and trafficking of proteins within cells, and has been implicated in various physiological and pathological states, including neurodegenerative diseases and cancer. Research has shown that VTA1 interacts with key components of the ESCRT (endosomal sorting complexes required for transport) machinery, which is essential for the proper multivesicular body formation and protein degradation. Recent studies have suggested that VTA1 might play a critical role in modulating cellular responses to stress and influencing cellular homeostasis. This has led to increased interest in its potential impact on disease mechanisms and its viability as a therapeutic target. The recombinant expression and characterization of VTA1 protein are crucial for elucidating its structure-function relationships and understanding its role in cellular dynamics. By producing VTA1 as a recombinant protein, researchers can perform biochemical assays, structural studies, and functional analyses that contribute to a more comprehensive understanding of its biological significance. Overall, the study of VTA1 and its recombinant form holds promise for uncovering new insights into intracellular trafficking processes and their implications in human health and disease.
