Analytical Data
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Gene name
ASMTL
- Application
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Alternative Names
ASMTL; ASMTLX; ASMTLY; ASTML; N acetylserotonin O methyltransferase like Protein
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O95671
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Expression Region
1-621aa
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AA Sequence
MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSKVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP
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Molecular Weight
95.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ASMTL (Arsenite Methyltransferase-Like) is a protein involved in various biological processes, including methylation reactions that play a crucial role in the detoxification of arsenic and other harmful metabolites. Given the increasing environmental and health concerns surrounding arsenic exposure, understanding the function and mechanism of ASMTL has gained significant research interest. Previous studies have implicated ASMTL in the regulation of cellular stress responses, contributing to the maintenance of cellular homeostasis and promoting cell survival under adverse conditions. Its role in methyl group transfer provides insights into how organisms adapt to toxic substances, potentially revealing novel therapeutic targets for arsenic toxicity. Additionally, ASMTL has been linked to various metabolic pathways, suggesting its involvement in broader physiological processes, such as lipid metabolism and epigenetic regulation. Recent advances in molecular biology and biochemistry have paved the way for a detailed characterization of ASMTL, including its structure, function, and interactions with other biomolecules. These insights could lead to improved understanding of not only arsenic-related health issues but also fundamental biological mechanisms relevant to various diseases. The ongoing research into ASMTL and its applications in medical and environmental contexts highlights the importance of continued exploration in this field, aiming to uncover the full potential of this fascinating protein in combating the effects of environmental toxins and understanding cellular resilience mechanisms.
