Analytical Data
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Gene name
ASB1
- Application
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Alternative Names
ASB1; KIAA1146Ankyrin repeat and SOCS box Protein 1; ASB-1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y576
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Expression Region
1-335aa
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AA Sequence
MAEGGSPDGR AGPGSAGRNL KEWLREQFCD HPLEHCEDTR LHDAAYVGDL QTLRSLLQEE SYRSRINEKS VWCCGWLPCT PLRIAATAGH GSCVDFLIRK GAEVDLVDVK GQTALYVAVV NGHLESTQIL LEAGADPNGS RHHRSTPVYH ASRVGRADIL KALIRYGADV DVNHHLTPDV QPRFSRRLTS LVVCPLYISA AYHNLQCFRL LLLAGANPDF NCNGPVNTQG FYRGSPGCVM DAVLRHGCEA AFVSLLVEFG ANLNLVKWES LGPESRGRRK VDPEALQVFK EARSVPRTLL CLCRVAVRRA LGKHRLHLIP SLPLPDPIKK FLLHE
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Molecular Weight
62.59 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ASB1 (Ankyrin Repeat and SOCS Box-Containing Protein 1) is a member of the ASB family of proteins, which play significant roles in various cellular processes, including signal transduction, protein degradation, and cellular regulation. The research into ASB1 has gained momentum due to its involvement in several critical biological functions, particularly in muscle development and immune responses. Studies have indicated that ASB1 can interact with several key signaling pathways, potentially influencing processes such as cell differentiation and apoptosis. Moreover, the dysregulation of ASB1 has been associated with various diseases, including cancer and autoimmune disorders. As a result, understanding the structure and function of ASB1, especially through the development of recombinant protein, has become a focal point for researchers aiming to delineate its precise roles in cellular mechanisms. The recombinant ASB1 protein serves as a valuable tool for investigating its interactions with other cellular proteins and pathways, providing insights into its functional implications in health and disease. This research not only enhances our comprehension of ASB1's biological significance but also opens potential avenues for therapeutic interventions targeting its pathways in various disorders.
