Analytical Data
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基因名
UBXN2B
- Application
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别名
UBXN2B；UBX domain-containing Protein 2B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14CS0
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表达区间
1-331aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMAEGGGPEPGEQERRSSGPRPPSARDL QLALAELYEDEVKCKSSKSNRPKATVFKSPRTPPQRFYSSEHEYSGLNIV RPSTGKIVNELFKEAREHGAVPLNEATRASGDDKSKSFTGGGYRLGSSFC KRSEYIYGENQLQDVQILLKLWSNGFSLDDGELRPYNEPTNAQFLESVKR GEIPLELQRLVHGGQVNLDMEDHQDQEYIKPRLRFKAFSGEGQKLGSLTP EIVSTPSSPEEEDKSILNAVVLIDDSVPTTKIQIRLADGSRLIQRFNSTH RILDVRNFIVQSRPEFAALDFILVTSFPNKELTDESLTLLEADILNTVLL QQLK
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分子量
40 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
UBXN2B is a protein that plays a significant role in various cellular processes, including the regulation of protein degradation and the management of cellular stress responses. It is part of the UBX domain-containing proteins, which are implicated in the ubiquitin-proteasome system (UPS) that controls protein turnover within the cell. Recent studies have highlighted UBXN2B's involvement in modulating autophagy and its potential implications in cancer biology and neurodegenerative diseases. As an accessory factor, UBXN2B can interact with different E3 ubiquitin ligases, thereby influencing the stability and activity of various target proteins. This has prompted research into the therapeutic potential of UBXN2B as a biomarker and target for drug development, especially in conditions where protein homeostasis is disrupted. Investigating the structure, function, and interactions of UBXN2B through recombinant protein studies aids in understanding its specific roles in cellular pathways and may lead to novel insights into disease mechanisms.
