Analytical Data
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Gene name
ARSE
- Application
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Alternative Names
ARSL; ARSE; QtrA-14484Arylsulfatase L; EC 3.1.6.-; Arylsulfatase E; ASE
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P51690
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Expression Region
1-589aa
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AA Sequence
MLHLHHSCLCFRSWLPAMLAVLLSLAPSASSDISASRPNILLLMADDLGIGDIGCYGNNTMRTPNIDRLAEDGVKLTQHISAASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGPPTNETTFAKILKEKGYATGLIGKWHLGLNCESASDHCHHPLHHGFDHFYGMPFSLMGDCARWELSEKRVNLEQKLNFLFQVLALVALTLVAGKLTHLIPVSWMPVIWSALSAVLLLASSYFVGALIVHADCFLMRNHTITEQPMCFQRTTPLILQEVASFLKRNKHGPFLLFVSFLHVHIPLITMENFLGKSLHGLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEGGIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTVVRLADSEVPQDRVIDGQDLLPLLLGTAQHSDHEFLMHYCERFLHAARWHQRDRGTMWKVHFVTPVFQPEGAGACYGRKVCPCFGEKVVHHDPPLLFDLSRDPSETHILTPASEPVFYQVMERVQQAVWEHQRTLSPVPLQLDRLGNIWRPWLQPCCGPFPLCWCLREDDPQ
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Molecular Weight
92.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ARSE (Arsenic Resistance Protein E) is a crucial protein implicated in the cellular response to arsenic exposure, which poses significant health risks as a toxic metalloid and environmental contaminant. Studies have increasingly highlighted the importance of ARSE in facilitating arsenic detoxification through its role in glutathione-mediated pathways. The research surrounding ARSE has gained momentum as scientists seek to unravel the molecular mechanisms governing arsenic resistance and the potential for therapeutic interventions in arsenic-related diseases. Characterizing the structure and function of ARSE could provide insights into its interactions with other cellular components and the pathways it influences, which may lead to novel strategies for enhancing resistance to arsenic toxicity. Given the rising concern over environmental arsenic contamination—particularly in regions reliant on groundwater for drinking purposes—understanding the biology of ARSE and its related mechanisms is imperative. Furthermore, insights from ARSE research could contribute to broader studies in cellular stress responses, metal ion homeostasis, and could also inform potential bioremediation strategies to mitigate arsenic's detrimental effects on health and the environment. Overall, ARSE represents a promising target for future research endeavors aimed at understanding arsenic resistance mechanisms and developing effective mitigation strategies.
