Analytical Data
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基因名
ARSE
- Application
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别名
ARSL; ARSE; QtrA-14484Arylsulfatase L; EC 3.1.6.-; Arylsulfatase E; ASE
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51690
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表达区间
1-589aa
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氨基酸序列
MLHLHHSCLCFRSWLPAMLAVLLSLAPSASSDISASRPNILLLMADDLGIGDIGCYGNNTMRTPNIDRLAEDGVKLTQHISAASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGPPTNETTFAKILKEKGYATGLIGKWHLGLNCESASDHCHHPLHHGFDHFYGMPFSLMGDCARWELSEKRVNLEQKLNFLFQVLALVALTLVAGKLTHLIPVSWMPVIWSALSAVLLLASSYFVGALIVHADCFLMRNHTITEQPMCFQRTTPLILQEVASFLKRNKHGPFLLFVSFLHVHIPLITMENFLGKSLHGLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEGGIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTVVRLADSEVPQDRVIDGQDLLPLLLGTAQHSDHEFLMHYCERFLHAARWHQRDRGTMWKVHFVTPVFQPEGAGACYGRKVCPCFGEKVVHHDPPLLFDLSRDPSETHILTPASEPVFYQVMERVQQAVWEHQRTLSPVPLQLDRLGNIWRPWLQPCCGPFPLCWCLREDDPQ
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分子量
92.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ARSE (Arsenic Resistance Protein E) is a crucial protein implicated in the cellular response to arsenic exposure, which poses significant health risks as a toxic metalloid and environmental contaminant. Studies have increasingly highlighted the importance of ARSE in facilitating arsenic detoxification through its role in glutathione-mediated pathways. The research surrounding ARSE has gained momentum as scientists seek to unravel the molecular mechanisms governing arsenic resistance and the potential for therapeutic interventions in arsenic-related diseases. Characterizing the structure and function of ARSE could provide insights into its interactions with other cellular components and the pathways it influences, which may lead to novel strategies for enhancing resistance to arsenic toxicity. Given the rising concern over environmental arsenic contamination—particularly in regions reliant on groundwater for drinking purposes—understanding the biology of ARSE and its related mechanisms is imperative. Furthermore, insights from ARSE research could contribute to broader studies in cellular stress responses, metal ion homeostasis, and could also inform potential bioremediation strategies to mitigate arsenic's detrimental effects on health and the environment. Overall, ARSE represents a promising target for future research endeavors aimed at understanding arsenic resistance mechanisms and developing effective mitigation strategies.
