Analytical Data
-
Gene name
PPP3Cb
- Application
-
Alternative Names
PPP3Cb；CALNA2；CALNB；CNA2；Serine/threonine-Protein phosphatase 2B catalytic subunit beta isoform
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P16298
-
Expression Region
2-524aa
-
AA Sequence
AAPEPARAA PPPPPPPPPP PGADRVVKAV PFPPTHRLTS EEVFDLDGIP RVDVLKNHLV KEGRVDEEIA LRIINEGAAI LRREKTMIEV EAPITVCGDI HGQFFDLMKL FEVGGSPANT RYLFLGDYVD RGYFSIECVL YLWVLKILYP STLFLLRGNH ECRHLTEYFT FKQECKIKYS ERVYEACMEA FDSLPLAALL NQQFLCVHGG LSPEIHTLDD IRRLDRFKEP PAFGPMCDLL WSDPSEDFGN EKSQEHFSHN TVRGCSYFYN YPAVCEFLQN NNLLSIIRAH EAQDAGYRMY RKSQTTGFPS LITIFSAPNY LDVYNNKAAV LKYENNVMNI RQFNCSPHPY WLPNFMDVFT WSLPFVGEKV TEMLVNVLSI CSDDELMTEG EDQFDGSAAA RKEIIRNKIR AIGKMARVFS VLREESESVL TLKGLTPTGM LPSGVLAGGR QTLQSATVEA IEAEKAIRGF SPPHRICSFE EAKGLDRINE RMPPRKDAVQ QDGFNSLNTA HATENHGTGN HTAQ
-
Molecular Weight
59 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPP3Cb, or protein phosphatase 3 catalytic subunit beta, is a critical enzyme involved in various cellular processes, including cell signaling, proliferation, and apoptosis. As a member of the serine/threonine phosphatase family, PPP3Cb plays a vital role in dephosphorylating key proteins modulated by calcium and calmodulin, which are crucial for maintaining cellular homeostasis and responding to external stimuli. Research has shown that dysregulation of PPP3Cb is implicated in numerous diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions. The study of PPP3Cb recombinant protein has gained significant attention, as it provides insights into its structure-function relationship, enzymatic activity, and regulatory mechanisms. By producing recombinant forms of PPP3Cb, researchers can explore its biochemical properties, identify potential inhibitors, and elucidate its role in pathological states. Furthermore, understanding how PPP3Cb interacts with other cellular components enhances the potential for developing targeted therapeutic strategies. Overall, the investigation of PPP3Cb recombinant protein is pivotal for advancing our knowledge of cell signaling pathways and uncovering novel approaches to treat diseases associated with its dysregulation.
