Analytical Data
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基因名
TRAF1
- Application
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别名
TRAF1；EBI6；TNF receptor-associated factor 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13077
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表达区间
1-416aa
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氨基酸序列
MASSSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGE DQICPKCRGEDLQSISPGSRLRTQEKAHPEVAEAGIGCPFAGVGCSFKGS PQSVQEHEVTSQTSHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQL QAAVEVAGDLEVDCYRAPCSESQEELALQHFMKEKLLAELEGKLRVFENI VAVLNKEVEASHLALATSIHQSQLDRERILSLEQRVVELQQTLAQKDQAL GKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAK YGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLL DQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAY VKDDTMFLKCIVETST
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分子量
74 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRAF1 (TNF Receptor Associated Factor 1) is a member of the TRAF protein family, which plays a crucial role in the signaling pathways of various receptors, particularly in the immune response and inflammation. Research has indicated that TRAF1 is involved in mediating signals from tumor necrosis factor (TNF) receptors, interleukin receptors, and other related cytokine receptors, thereby influencing cellular processes such as survival, proliferation, and differentiation. Its expression has been linked to various diseases, including autoimmune disorders and cancer, making it a significant focus of study for therapeutic interventions. Moreover, TRAF1's interaction with other signaling proteins highlights its potential as a regulatory hub within the immune system. Recombinant TRAF1 protein studies provide insights into its structural and functional properties, enhancing our understanding of its role in inflammatory processes and disease pathogenesis. As researchers explore TRAF1's mechanisms of action, they aim to develop novel strategies for modulating its activity, which could lead to new treatments for inflammation-related diseases and cancer. Overall, TRAF1 represents a compelling target for further investigation, given its multifaceted involvement in immune regulation and its potential implications in clinical applications.
