Analytical Data
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Gene name
OSBPL6
- Application
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Alternative Names
FLJ36583; ORP 6; ORP-6; ORP6; OSBL6_HUMAN; OSBP-related protein 6; OSBPL 6; Osbpl6; Oxysterol Binding Protein like 6; Oxysterol-binding protein-related protein 6
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BZF3
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Expression Region
1-508 aa
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AA Sequence
MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQSMHHLSFQVVLSTCQIATRRLNEQAFPLPRHPHPC
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Molecular Weight
83.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
OSBPL6 (Oxysterol binding protein-like 6) is a member of the OSBP family, which plays a crucial role in lipid metabolism and cellular signaling. Research into OSBPL6 has gained significance due to its involvement in various biological processes, including cholesterol homeostasis, membrane trafficking, and response to oxidative stress. As a lipid-binding protein, OSBPL6 participates in the transport of oxysterols and other lipids, which are critical for maintaining cellular functions and signaling pathways. Dysregulation of OSBPL6 has been implicated in several diseases, including metabolic disorders, cardiovascular diseases, and neurodegenerative conditions. Understanding the structure and function of OSBPL6 is essential for elucidating its role in health and disease. Recent studies have focused on characterizing its protein interactions, regulatory mechanisms, and potential as a therapeutic target. Moreover, the recombinant expression of OSBPL6 offers a valuable tool for investigating its functional properties and exploring its potential applications in drug discovery and development. The ongoing examination of OSBPL6’s molecular mechanisms and its impact on lipid-related diseases highlights its emerging importance in biomedical research.
