Analytical Data
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Gene name
TNFAIP8
- Application
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Alternative Names
TNFAIP8;Tumor necrosis factor alpha-induced Protein 8-like Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O95379
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Expression Region
2-198aa
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AA Sequence
HSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKMLDEENI
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Molecular Weight
49.9kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TNFAIP8 (Tumor Necrosis Factor Alpha Induced Protein 8) is a critical protein implicated in various cellular processes, including immune response, inflammation, and tumorigenesis. Characterized as an early response gene to TNF-α stimulation, TNFAIP8 has garnered attention due to its involvement in regulating cell survival, apoptosis, and metabolism. Research indicates that TNFAIP8 plays a significant role in maintaining cellular homeostasis and has been linked to various diseases, including cancer, where it is often overexpressed in malignant tissues. Understanding the function and mechanisms of TNFAIP8 is essential for deciphering its role in pathophysiology and developing potential therapeutic strategies. Recent studies employing recombinant TNFAIP8 have aimed to elucidate its structure-function relationships and explore its interaction with other cellular pathways. By producing and analyzing recombinant TNFAIP8, researchers seek to assay its properties, such as its effects on apoptosis, cellular signaling, and its potential as a biomarker or therapeutic target in diseases characterized by dysregulated inflammation and tumor growth. This research not only sheds light on the biological significance of TNFAIP8 but also opens avenues for innovative treatment modalities against TNF-α related disorders and cancer.











