Cat: PA2000-5538

Recombinant Human APOBEC1 Protein,His

  • Price
  • Size
  • Number

    Order now. For delivery time, please consult customer service

  • Pre-sale guidance and worry-free after-sale service
  • Quality assurance for cold chain transportation

Analytical Data

  • Gene name

    APOBEC1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    BEDP; C->U-editing enzyme APOBEC-1; CDAR1; EC 3.5.4.; HEPR

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P41238

  • Expression Region

    1-236aa

  • AA Sequence

    MTSEKGPSTG DPTLRRRIEP WEFDVFYDPR ELRKEACLLY EIKWGMSRKI WRSSGKNTTN HVEVNFIKKF TSERDFHPSM SCSITWFLSW SPCWECSQAI REFLSRHPGV TLVIYVARLF WHMDQQNRQG LRDLVNSGVT IQIMRASEYY HCWRNFVNYP PGDEAHWPQY PPLWMMLYAL ELHCIILSLP PCLKISRRWQ NHLTFFRLHL QNCHYQTIPP HILLATGLIH PSVAWR

  • Molecular Weight

    28.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

Related Products

Protein Description

APOBEC1, a member of the APOBEC (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) family, plays a crucial role in RNA editing, particularly in the conversion of cytidine to uridine in apolipoprotein B mRNA, which regulates lipid metabolism and contributes to various metabolic disorders. Originally identified for its function in editing mRNA, research has expanded to explore APOBEC1's involvement in immune responses, especially in antiviral defense and host recognition of viral RNA. Additionally, studies have revealed that APOBEC1 can influence genomic stability through its deaminase activity, which has implications in cancer biology, as aberrant activity may lead to mutagenesis and tumor development. Understanding the structural and functional characteristics of recombinant APOBEC1 is pivotal for elucidating its mechanisms of action and potential therapeutic targeting. Researchers aim to investigate the protein's enzymatic activity, substrate specificity, and interaction with other cellular factors, paving the way for innovative approaches in treating metabolic disorders and malignancies associated with APOBEC1 dysregulation. This multifaceted research approach highlights the significance of detailed studies on recombinant APOBEC1 to unlock its potential in both basic and translational science.

E-mail

sales@ipodix.com

Sales

+1 2092920560


Contact us via WhatsApp

IPODIX Biotech Inc

2108 N ST, STE N
Sacramento, CA 95816, USA

For Product Information and Orders

sales@ipodix.com

For Business Collaboration

sales@ipodix.com

For CRO Services

sales@ipodix.com

For Technical Support

sales@ipodix.com
  • 50000+

    Recombinant Proteins

  • 100+

    Researchers

  • 100+

    Countries Served

  • ISO

    Certified Quality

Committed to Quality
Driven by Innovation

Learn More About US