Analytical Data
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基因名
ANXA2R
- Application
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别名
Annexin 2 receptor; Annexin II receptor; Annexin-2 receptor; ANXA2R; AX2R; AX2R_HUMAN; AXIIR; C5orf39; Chromosome 5 open reading frame 39; LOC389289
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q3ZCQ2
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表达区间
1-193aa
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氨基酸序列
MEQHFLGCVK RAWDSAEVAP EPQPPPIVSS EDRGPWPLPL YPVLGEYSLD SCDLGLLSSP CWRLPGVYWQ NGLSPGVQST LEPSTAKPTE FSWPGTQKQQ EAPVEEVGQA EEPDRLRLQQ LPWSSPLHPW DRQQDTEVCD SGCLLERRHP PALQPWRHLP GFSDCLEWIL RVGFAAFSVL WACCSRICGA KQP
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分子量
21.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ANXA2R, or Annexin A2 receptor, plays a significant role in various cellular processes, including signal transduction, endocytosis, and inflammation. It is recognized for binding to its ligand, annexin A2, which is implicated in multiple physiological and pathological conditions, such as cancer progression and cardiovascular diseases. Research into ANXA2R has gained momentum due to its potential as a therapeutic target; altered expression and function of ANXA2R in different cancers make it a candidate for biomarker development and targeted therapies. Furthermore, understanding the molecular mechanisms of ANXA2R interactions can provide insights into its involvement in disease progression. The development of recombinant ANXA2R proteins has been essential for elucidating these mechanisms. By producing these proteins in a controlled laboratory setting, researchers can investigate the receptor's structure-function relationships, identify potential inhibitors, and explore its signaling pathways in detail. This foundational research is crucial for creating innovative therapeutic strategies aimed at modulating ANXA2R activity in various diseases, thus highlighting the importance of recombinant ANXA2R proteins in modern biomedical research.
