Cat: PA1000-3196

Recombinant Human THRSP Protein,His

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Analytical Data

  • 基因名

    THRSP

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    THRSP;Thyroid hormone-inducible hepatic Protein

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q92748

  • 表达区间

    1-146aa

  • 氨基酸序列

    MQVLTKRYPKNCLLTVMDRYAAEVHNMEQVVMIPSLLRDVQLSGPGGQAQAEAPDLYTYFTMLKAICVDVDHGLLPREEWQAKVAGSEENGTAETEEVEDESASGELDLEAQFHLHFSSLHHILMHLTEKAQEVTRKYQEMTGQVW

  • 分子量

    43.6kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

THRSP (Thyroid Hormone Responsive Protein), also known as Spot14, is a protein that plays a significant role in the regulation of lipid metabolism and fatty acid synthesis. Originally identified as a thyroid hormone-responsive gene, THRSP is primarily expressed in adipose tissue and liver, and it has been implicated in energy homeostasis. Its involvement in metabolic processes makes it an important target for research, particularly in the context of obesity and metabolic disorders. Studies have shown that THRSP is regulated by various hormonal signals and nutritional states, suggesting it acts as a sensor of metabolic changes. Furthermore, THRSP can influence the expression of genes associated with lipogenesis and can modulate the action of transcription factors involved in fatty acid metabolism. Given the rising prevalence of metabolic diseases, researchers are increasingly focused on understanding the molecular mechanisms underlying THRSP's functions. This includes exploring its role in energy balance, its potential as a therapeutic target for obesity, and its interactions with other metabolic pathways. Advances in recombinant protein technologies have facilitated the study of THRSP, providing insights into its structure and function. By generating recombinant THRSP, researchers can investigate its biological activity, interactions with other proteins, and effects on metabolic regulation in a controlled environment. Overall, THRSP holds promise as a key player in the understanding and treatment of metabolic diseases, making it a focal point of ongoing biomedical research.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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