Analytical Data
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Gene name
ANP32B
- Application
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Alternative Names
Acidic (leucine rich) nuclear phosphoProtein 32 family member B; Acidic leucine rich nuclear phosphoProtein 32 family member B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92688
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Expression Region
1-251aa
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AA Sequence
MDMKRRIHLE LRNRTPAAVR ELVLDNCKSN DGKIEGLTAE FVNLEFLSLI NVGLISVSNL PKLPKLKKLE LSENRIFGGL DMLAEKLPNL THLNLSGNKL KDISTLEPLK KLECLKSLDL FNCEVTNLND YRESVFKLLP QLTYLDGYDR EDQEAPDSDA EVDGVDEEEE DEEGEDEEDE DDEDGEEEEF DEEDDEDEDV EGDEDDDEVS EEEEEFGLDE EDEDEDEDEE EEEGGKGEKR KRETDDEGED D
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Molecular Weight
28.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ANP32B, a member of the acidic nuclear phosphoprotein (ANP) family, has garnered significant attention in recent years due to its pivotal role in various cellular processes, including cell proliferation, differentiation, and apoptosis. As a highly conserved protein, ANP32B participates in the regulation of histone acetylation and chromatin remodeling, thereby influencing gene expression. Its involvement in the modulation of the p53 signaling pathway further underscores its importance in tumorigenesis and cancer progression. Abnormal expression levels of ANP32B have been implicated in various diseases, making it a potential biomarker for diagnosis and prognosis. Recent studies utilizing recombinant ANP32B have aimed to elucidate its functional mechanisms and interactions within the cell. By expressing this protein in a controlled environment, researchers can probe its structural properties and investigate its role in complex signaling networks. The development of recombinant ANP32B is thus essential for advancing our understanding of its biological significance and therapeutic potential. As knowledge of this protein expands, it holds promise for the identification of novel therapeutic targets in cancer and other diseases characterized by dysregulated cellular processes.
