Analytical Data
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基因名
THG1L
- Application
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别名
THG1L；ICF45；Probable tRNA(His) guanylyltransferase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NWX6
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表达区间
30-298aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMAKSKFE YVRDFEADDT CLAHCWVVVR LDGRNFHRFA EKHNFAKPND SRALQLMTKC AQTVMEELED IVIAYGQSDE YSFVFKRKTN WFKRRASKFM THVASQFASS YVFYWRDYFE DQPLLYPPGF DGRVVVYPSN QTLKDYLSWR QADCHINNLY NTVFWALIQQ SGLTPVQAQG RLQGTLAADK NEILFSEFNI NYNNELPMYR KGTVLIWQKV DEVMTKEIKL PTEMEGKKMA VTRTRTKPVP LHCDIIGDAF WKEHPEILDE DS
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分子量
34 kD
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
THG1L (Thymidine Kinase 1-Like Protein) is an intriguing member of the thymidine kinase family, primarily known for its role in nucleotide metabolism. The research on THG1L has gained traction due to its emerging implications in various biological processes and diseases, including cancer and neurodegenerative disorders. Unlike classical thymidine kinases, THG1L is speculated to participate in RNA metabolism, potentially influencing cellular responses to stress and playing a role in the regulation of gene expression. Its unique structure and enzymatic properties suggest that it may serve as a critical player in the balance between cell proliferation and apoptosis. By studying the recombinant form of THG1L, researchers aim to elucidate its functional mechanisms and interactions within the cell. Understanding THG1L's role is crucial for developing targeted therapeutics and advancing our knowledge of cellular biology, particularly in the context of tumorigenesis and cellular aging. The recombinant protein presents opportunities for structural biology studies, enzyme kinetics, and drug design, laying the groundwork for future research that may uncover novel therapeutic strategies leveraging THG1L's biochemical pathways. Overall, the investigation into THG1L's recombinant protein not only highlights its potential significance in health and disease but also opens avenues for innovative approaches in biomedical research.
