Analytical Data
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Gene name
OR8B8
- Application
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Alternative Names
OR8B8; Olfactory receptor 8B8; Olfactory receptor TPCR85; Olfactory-like receptor JCG8
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15620
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Expression Region
1-311 aa
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AA Sequence
MAAENSSFVTQFILAGLTDQPGVQIPLFFLFLGFYVVTVVGNLGLITLIRLNSHLHTPMY FFLYNLSFIDFCYSSVITPKMLMSFVLKKNSISYAGCMTQLFFFLFFVVSESFILSAMAY DRYVAICNPLLYMVTMSPQVCFLLLLGVYGMGFAGAMAHTACMMGVTFCANNLVNHYMCD ILPLLECACTSTYVNELVVFVVVGIDIGVPTVTIFISYALILSSIFHIDSTEGRSKAFST CSSHIIAVSLFFGSGAFMYLKPFSLLAMNQGKVSSLFYTTVVPMLNPLIYSLRNKDVKVA LKKILNKNAFS
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Molecular Weight
34.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The OR8B8 gene encodes an olfactory receptor that is part of the extensive family of G protein-coupled receptors (GPCRs) responsible for the detection of odorants. Understanding the function of OR8B8 is critical due to its potential involvement in human sensory perception and its implications for research in neurobiology and olfactory signaling pathways. Recent studies have indicated that certain olfactory receptors, including OR8B8, may play a role beyond mere odor detection, potentially influencing behaviors and physiological responses. Additionally, with advances in recombinant protein technology, the production of OR8B8 as a soluble protein allows researchers to study its structure and function in greater detail, opening avenues for potential therapeutic applications. The investigation of OR8B8 also contributes to the broader understanding of the olfactory system's complexity and its evolutionary significance across different species. Insights gained from OR8B8 research may also have implications for understanding anosmia (loss of smell) and other sensory processing disorders, thus highlighting its relevance in both basic and applied research in olfactory biology and pharmacology.
