Cat: PA2000-5513

Recombinant Human ANKS1 Protein,GST

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Analytical Data

  • Gene name

    ANKS1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ANKS 1; ANKS 1A; ANKS1; ANKS1A; Ankyrin repeat and SAM domain containing 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q92625

  • Expression Region

    1-460aa

  • AA Sequence

    MSSIGEGIDFSQERQKISGSRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN

  • Molecular Weight

    77.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ANKS1 (ANKS1A) is a protein that plays a crucial role in various cellular processes, including signal transduction, cytoskeletal organization, and cell adhesion. The research on ANKS1 has gained traction due to its involvement in key biological functions, particularly in the context of development and disease mechanisms. Recent studies have suggested that ANKS1 may be linked to neurodevelopmental disorders and cancer, highlighting its potential as a biomarker for disease progression and a target for therapeutic intervention. Given its significance, researchers are focusing on the recombinant production of ANKS1 protein to facilitate in-depth studies of its structure, function, and interactions with other cellular components. Recombinant ANKS1 protein can be utilized in various assays to elucidate its role in signaling pathways and its response to cellular stress, thereby providing insights into its physiological and pathological implications. The ongoing investigations aim to clarify the molecular mechanisms that underlie ANKS1's effects on cell behavior, which may pave the way for innovative strategies in the treatment of related diseases.

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