Cat: PAX2000-10019

Recombinant Human OR8A1 Protein,His

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Analytical Data

  • Gene name

    OR8A1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    OR8A1; Olfactory receptor 8A1; OST025; Olfactory receptor OR11-318

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8NGG7

  • Expression Region

    1-326 aa

  • AA Sequence

    MGFLSPMHPCRPPTQRRMAAGNHSTVTEFILKGLTKRADLQLPLFLLFLGIYLVTIVGNL GMITLICLNSQLHTPMYYFLSNLSLMDLCYSSVITPKMLVNFVSEKNIISYAGCMSQLYF FLVFVIAECYMLTVMAYDRYVAICHPLLYNIIMSHHTCLLLVAVVYAIGLIGSTIETGLM LKLPYCEHLISHYFCDILPLMKLSCSSTYDVEMTVFFSAGFNIIVTSLTVLVSYTFILSS ILGISTTEGRSKAFSTCSSHLAAVGMFYGSTAFMYLKPSTISSLTQENVASVFYTTVIPM LNPLIYSLRNKEVKAAVQKTLRGKLF

  • Molecular Weight

    36.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

OR8A1 is a member of the olfactory receptor gene family, which plays a crucial role in the perception of odorant molecules. As a G protein-coupled receptor (GPCR), OR8A1 is expressed in sensory neurons of the olfactory epithelium and is involved in the transduction of odor signals to the brain, thereby influencing smell perception and behavior. Research on OR8A1 and its recombinant proteins is essential for understanding the molecular mechanisms of olfaction, as well as the functional roles of specific receptors in recognizing diverse odorant structures. Given the substantial genetic variability among olfactory receptor genes, studying the recombinant OR8A1 protein allows scientists to elucidate the structure-activity relationship of this receptor and its interactions with various odorants. Moreover, OR8A1 has been implicated in certain physiological processes and potential implications in neurodegenerative diseases and conditions affecting the olfactory system. Ultimately, investigating recombinant OR8A1 not only provides insights into fundamental sensory biology but also holds potential applications in developing olfactory-related therapies and enhancing fragrance industry products.

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