Analytical Data
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基因名
TGIF2LY
- Application
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别名
TGIF2LY;TGIFLY;Homeobox Protein TGIF2LY
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IUE0
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表达区间
1-185aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMEAAADG PAETQSPVEK DSPAKTQSPA QDTSIMSRNN ADTGRVLALP EHKKKRKGNL PAESVKILRD WMYKHRFKAY PSEEEKQMLS EKTNLSLLRI SNWFINARRR ILPDMLQQRR NDPIIGHKTG KDAHATHLQS TEASVPAKSG PVVQTMYKAC PCGPCQRARC QERSNQIRSR PLARSSPE
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分子量
23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The TGIF2LY (TG-interacting factor 2 like Y-linked) protein is a member of the TGIF family of transcriptional co-regulators, which play significant roles in various biological processes, including embryonic development and cellular differentiation. Research on TGIF2LY is particularly intriguing due to its Y-linked inheritance pattern, which raises questions about its functional implications in sexual differentiation and potential implications in male-specific diseases. Recent studies have suggested that TGIF2LY may be involved in regulating gene expression by influencing transcriptional pathways, notably within the context of developmental signaling pathways such as TGF-beta and Wnt. The protein is hypothesized to modulate cellular responses to these signals, contributing to the fine-tuning of gene regulation during critical developmental phases. Understanding the structure and function of TGIF2LY at the molecular level, including its interactions with other proteins and DNA, could reveal insights into its role in health and disease. Given the increasing interest in the impact of Y-linked genes on male physiology and pathologies, exploring TGIF2LY's mechanisms of action offers promising avenues for further research, potentially uncovering novel therapeutic targets for conditions linked to dysfunctions in these pathways. This makes TGIF2LY a compelling subject for genomic and proteomic studies aimed at deciphering its unique contributions to normal biological function and its potential involvement in disorders rooted in chromosomal anomalies. As such, the investigation of TGIF2LY not only enriches our understanding of genetic regulation but also highlights the complex interplay between sex-linked genes and various biological phenomena.












