Analytical Data
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Gene name
TGIF2LY
- Application
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Alternative Names
TGIF2LY；TGIFLY；Homeobox Protein TGIF2LY
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IUE0
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Expression Region
1-185aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMEAAADG PAETQSPVEK DSPAKTQSPA QDTSIMSRNN ADTGRVLALP EHKKKRKGNL PAESVKILRD WMYKHRFKAY PSEEEKQMLS EKTNLSLLRI SNWFINARRR ILPDMLQQRR NDPIIGHKTG KDAHATHLQS TEASVPAKSG PVVQTMYKAC PCGPCQRARC QERSNQIRSR PLARSSPE
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Molecular Weight
23 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The TGIF2LY (TG-interacting factor 2 like Y-linked) protein is a member of the TGIF family of transcriptional co-regulators, which play significant roles in various biological processes, including embryonic development and cellular differentiation. Research on TGIF2LY is particularly intriguing due to its Y-linked inheritance pattern, which raises questions about its functional implications in sexual differentiation and potential implications in male-specific diseases. Recent studies have suggested that TGIF2LY may be involved in regulating gene expression by influencing transcriptional pathways, notably within the context of developmental signaling pathways such as TGF-beta and Wnt. The protein is hypothesized to modulate cellular responses to these signals, contributing to the fine-tuning of gene regulation during critical developmental phases. Understanding the structure and function of TGIF2LY at the molecular level, including its interactions with other proteins and DNA, could reveal insights into its role in health and disease. Given the increasing interest in the impact of Y-linked genes on male physiology and pathologies, exploring TGIF2LY's mechanisms of action offers promising avenues for further research, potentially uncovering novel therapeutic targets for conditions linked to dysfunctions in these pathways. This makes TGIF2LY a compelling subject for genomic and proteomic studies aimed at deciphering its unique contributions to normal biological function and its potential involvement in disorders rooted in chromosomal anomalies. As such, the investigation of TGIF2LY not only enriches our understanding of genetic regulation but also highlights the complex interplay between sex-linked genes and various biological phenomena.
