Analytical Data
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基因名
TGFBRAP1
- Application
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别名
TGFBRAP1；Transforming growth factor-beta receptor-associated Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WUH2
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表达区间
601-860aa
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氨基酸序列
RGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSKRLQKEEYHTHLAVL YLEEVLLQRASASGKGAEATETQAKLRRLLQKSDLYRVHFLLERLQGAGL PMESAILHGKLGEHEKALHILVHELQDFAAAEDYCLWCSEGRDPPHRQQL FHTLLAIYLHAGPTAHELAVAAVDLLNRHATEFDAAQVLQMLPDTWSVQL LCPFLMGAMRDSIHARRTMQVALGLARSENLIYTYDKMKLKGSSIQLSDK KLCQICQNPFCEPVFVRYPNGGLVHTHCAASRHTNPSSSSPGTRT
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分子量
33 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TGFBRAP1, or TGF-beta receptor-associated protein 1, is a crucial protein that plays a significant role in the signaling pathways mediated by Transforming Growth Factor-beta (TGF-β). This protein has garnered attention in recent years due to its involvement in various cellular processes, including epithelial-to-mesenchymal transition (EMT), cell differentiation, and the regulation of immune responses. Dysregulation of TGFBRAP1 has been implicated in several pathological conditions, including fibrosis and cancer, where it may contribute to tumor progression and metastasis. Research focusing on the recombinant expression of TGFBRAP1 has become increasingly important as it allows for the investigation of its structure-function relationships and interactions with other proteins involved in TGF-β signaling. Recombined TGFBRAP1 can be used in various in vitro and in vivo studies to elucidate its biological functions, validate its role as a potential therapeutic target, and explore its interactions within the broader context of TGF-β signaling networks. This understanding could lead to innovative approaches for targeted therapies in diseases where TGFBRAP1 plays a crucial role, making it a significant focus within the fields of molecular biology and translational medicine.
