Analytical Data
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Gene name
BSN
- Application
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Alternative Names
BSN；KIAA0434；ZNF231；Protein bassoon
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UPA5
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Expression Region
全长
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AA Sequence
full
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Molecular Weight
416 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BSN (Bassoon) is a crucial presynaptic protein involved in neurotransmitter release and synaptic architecture, playing a significant role in the organization of the active zone at synapses. Research on BSN recombinant proteins has gained momentum due to its essential functions in synaptic transmission and plasticity, which are critical for learning and memory processes. Abnormalities in BSN expression and function have been linked to various neurological disorders, including schizophrenia and autism spectrum disorders. By producing BSN as a recombinant protein, researchers aim to elucidate its structural and functional properties, investigating how it interacts with other synaptic proteins and contributes to synaptic stability and efficiency. The study of BSN not only enhances our understanding of synaptic mechanisms but also holds potential therapeutic implications for neurodevelopmental disorders. Advances in protein engineering and expression systems have facilitated the generation of high-purity recombinant BSN, allowing for detailed biochemical assays and structural analyses. This research is pivotal in unraveling the complex interplay of proteins at synapses and the broader implications for neural circuit function and dysfunction.
