Analytical Data
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Gene name
ALX4
- Application
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Alternative Names
Alx4; ALX4_HUMAN; Aristaless like homeobox 4; CRS5; FND2; FPP
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H161
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Expression Region
1-411aa
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AA Sequence
MNAETCVSYC ESPAAAMDAY YSPVSQSREG SSPFRAFPGG DKFGTTFLSA AAKAQGFGDA KSRARYGAGQ QDLATPLESG AGARGSFNKF QPQPSTPQPQ PPPQPQPQQQ QPQPQPPAQP HLYLQRGACK TPPDGSLKLQ EGSSGHSAAL QVPCYAKESS LGEPELPPDS DTVGMDSSYL SVKEAGVKGP QDRASSDLPS PLEKADSESN KGKKRRNRTT FTSYQLEELE KVFQKTHYPD VYAREQLAMR TDLTEARVQV WFQNRRAKWR KRERFGQMQQ VRTHFSTAYE LPLLTRAENY AQIQNPSWLG NNGAASPVPA CVVPCDPVPA CMSPHAHPPG SGASSVTDFL SVSGAGSHVG QTHMGSLFGA ASLSPGLNGY ELNGEPDRKT SSIAALRMKA KEHSAAISWA T
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Molecular Weight
44 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ALX4, a member of the ALX homeobox gene family, plays a crucial role in the development and differentiation of various tissues, particularly in the craniofacial region. It is predominantly expressed in embryonic tissues during critical stages of development, influencing cell migration, proliferation, and patterning. Mutations in the ALX4 gene have been associated with disorders such as craniosynostosis and other congenital anomalies, highlighting its significance in developmental biology. The study of ALX4 recombinant proteins has gained attention as a means to elucidate its functional mechanisms and interactions with other cellular pathways. Researchers are exploring the use of recombinant ALX4 to investigate its biochemical properties, regulatory functions, and potential as a therapeutic target. The recombinant protein can serve as a valuable tool in understanding the molecular underpinnings of craniofacial developmental processes and may pave the way for novel strategies in regenerative medicine and gene therapy aimed at correcting developmental defects associated with ALX4 dysregulation. Ultimately, this research not only expands our knowledge of the role of homeobox genes in development but also opens avenues for innovative treatments for genetic disorders linked to ALX4.
