Analytical Data
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基因名
ALX3
- Application
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别名
ALX3Homeobox Protein aristaless-like 3; Proline-rich transcription factor ALX3
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95076
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表达区间
1-343aa
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氨基酸序列
MDPEHCAPFRVGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGIYSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT
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分子量
36.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ALX3, a member of the ALX (Aly-class homeobox) gene family, plays a crucial role in embryonic development and tissue patterning. It is involved in regulatory processes that govern organogenesis and cell differentiation, particularly in the development of the pancreas, intestine, and other organs. Research into the ALX3 recombinant protein has gained interest due to its potential implications in understanding congenital malformations and diseases associated with ALX3 dysfunction, including certain types of cancer and developmental disorders. By investigating the structure and functional properties of ALX3, scientists aim to elucidate the molecular mechanisms underlying its role in development. The recombinant form of ALX3 can be produced using various expression systems, allowing for in-depth functional assays, protein-protein interaction studies, and high-throughput screening of small molecule inhibitors or modulators. These studies are vital for developing therapeutic approaches that could potentially target ALX3-related pathways, offering avenues for intervention in diseases where ALX3 is implicated. The growing body of knowledge surrounding the ALX3 protein not only enhances our understanding of its biological significance but also helps identify its potential as a biomarker for certain conditions, paving the way for innovative treatments in regenerative medicine and oncology.
