Analytical Data
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基因名
SYNJ2BP
- Application
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别名
SYNJ2BP;OMP25;Synaptojanin-2-binding Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P57105
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表达区间
1-145aa
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氨基酸序列
MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQ EGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEGDPSGIPI FMVLVPVFALTMVAAWAFMRYRQQL
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SYNJ2BP (Synaptojanin 2 Binding Protein) is a crucial molecule implicated in synaptic function and neuronal signaling. Its research background highlights its role in the endocytic pathway, where it interacts with proteins involved in synapse formation and maintenance. Studies indicate that SYNJ2BP may play a significant role in regulating neurotransmitter release and recycling synaptic vesicles, thereby influencing overall synaptic plasticity. Furthermore, its association with neurodevelopmental and neurodegenerative disorders has sparked interest among researchers, as mutations or dysregulation of SYNJ2BP can lead to impairments in cognition and behavior. Recent investigations have focused on the structural analysis and functional characterization of SYNJ2BP to unveil its interaction networks and molecular mechanisms. The recombinant protein of SYNJ2BP has been utilized in various assays to study its binding properties and contributions to synaptic activity. Understanding the dynamics of SYNJ2BP and its pathways is essential for elucidating its roles in healthy neuronal function and in the pathogenesis of related disorders.












