Analytical Data
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Gene name
STX3
- Application
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Alternative Names
STX3；STX3A；Syntaxin-3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13277
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Expression Region
1-263aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMMKDRL EQLKAKQLTQ DDDTDAVEIA IDNTAFMDEF FSEIEETRLN IDKISEHVEE AKKLYSIILS APIPEPKTKD DLEQLTTEIK KRANNVRNKL KSMEKHIEED EVRSSADLRI RKSQHSVLSR KFVEVMTKYN EAQVDFRERS KGRIQRQLEI TGKKTTDEEL EEMLESGNPA IFTSGIIDSQ ISKQALSEIE GRHKDIVRLE SSIKELHDMF MDIAMLVENQ GEMLDNIELN VMHTVDHVEK ARDETKKAVK YQSQARKK
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Molecular Weight
33 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STX3, or Syntaxin 3, is a member of the syntaxin family of proteins, which are integral components of the vesicle trafficking and fusion machinery in eukaryotic cells. As a t-SNARE (target soluble N-ethylmaleimide-sensitive factor attachment protein receptor), STX3 plays a critical role in mediating the fusion of transport vesicles with their target membranes, facilitating the transport of proteins and lipids within cells. Research into STX3 has gained momentum due to its involvement in various physiological processes, including neuronal communication and immune responses. Abnormalities in STX3 expression or function have been implicated in several diseases, including neurodegenerative disorders and certain cancers. Recombinant STX3 proteins have been developed to study their structural properties and functional mechanisms in vitro. These studies aim to elucidate the specific interactions STX3 engages in during vesicle fusion and to explore its potential as a therapeutic target. The ongoing investigation into STX3 not only enhances our understanding of cellular transport mechanisms but also opens new avenues for the development of biomedical interventions targeting vesicle trafficking pathways.
