Analytical Data
-
Gene name
STK3
- Application
-
Alternative Names
STK3；KRS1；Serine/threonine-Protein kinase 3
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q13188
-
Expression Region
2-491aa
-
AA Sequence
EQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ VVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEY CGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGN ILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCV ADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDF TDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKR HEEQQRELEEEEENSDEDELDSHTMVKTSVESVGTMRATSTMSEGAQTMI EHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQD FKNKSHENCNQNMHEPFPMSKNVFPDNWKVPQDGDFDFLKNLSLEELQMR LKALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF
-
Molecular Weight
78 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STK3, also known as Serine/Threonine Kinase 3, is a member of the mitogen-activated protein kinase (MAPK) superfamily and plays a crucial role in cellular signaling pathways that regulate various biological processes, including cell growth, differentiation, and apoptosis. Research into STK3 has gained prominence due to its involvement in tumorigenesis and cancer progression, particularly in relation to its function as a mediator of stress responses and its potential role as a tumor suppressor. The study of recombinant STK3 protein has become essential for understanding its biochemical properties, regulatory mechanisms, and interactions with other signaling molecules. By expressing STK3 in a recombinant system, researchers aim to produce sufficient quantities of the protein for detailed structural and functional analyses. This knowledge is vital for elucidating STK3's role in various signaling cascades and its potential as a therapeutic target for cancer treatment. Additionally, understanding the modulation of STK3 activity could provide insights into novel strategies for the development of kinase inhibitors, which are increasingly being explored in the context of personalized medicine. Thus, recombinant STK3 protein serves as a pivotal tool in both basic and translational research aimed at unraveling the complex web of signaling networks that govern cellular behavior in health and disease.
