Analytical Data
-
Gene name
STARD5
- Application
-
Alternative Names
STARD5；StAR-related lipid transfer Protein 5
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9NSY2
-
Expression Region
1-213aa
-
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMDPALAA QMSEAVAEKM LQYRRDTAGW KICREGNGVS VSWRPSVEFP GNLYRGEGIV YGTLEEVWDC VKPAVGGLRV KWDENVTGFE IIQSITDTLC VSRTSTPSAA MKLISPRDFV DLVLVKRYED GTISSNATHV EHPLCPPKPG FVRGFNHPCG CFCEPLPGEP TKTNLVTFFH TDLSGYLPQN VVDSFFPRSM TRFYANLQKA VKQFHE
-
Molecular Weight
26 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STARD5, or Steroidogenic Acute Regulatory Domain 5, is a member of the START (StAR-related lipid transfer) protein family, which plays a critical role in lipid transport and hormone biosynthesis. This protein is primarily studied for its function in the transport of cholesterol to mitochondria, a key step in steroidogenesis, which is vital for the production of steroid hormones such as cortisol, aldosterone, and sex steroids. Research has shown that STARD5 is involved in various physiological processes, including cellular signaling and metabolic regulation. Dysregulation of STARD5 expression has been implicated in several diseases, including adrenal disorders and certain cancers, making it a potential biomarker for disease progression and a target for therapeutic intervention. The study of STARD5 recombinant proteins provides insight into its structural and functional properties, enabling the exploration of its lipid-binding capabilities and interaction with other cellular molecules. Understanding the mechanisms underlying STARD5 function could have significant implications for developing new treatments for disorders linked to steroid hormone imbalances and metabolic dysregulation. Therefore, research on STARD5 recombinant proteins is crucial for uncovering the molecular intricacies of steroid hormone synthesis and its associated pathological conditions.
