Analytical Data
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基因名
CDH18
- Application
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别名
CDH18；CDH14；Cadherin-18
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13634
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表达区间
54-608aa
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氨基酸序列
MASMTGGQQMGRGHHHHHHGNLYFQGGEFGWVWNQFFVLEEHMGPDPQYV GKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHY VLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDM GTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNM DREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQ LYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKET REGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIV GDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYN VEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTV GIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFN FFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGG IPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSS
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分子量
65 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDH18, or Cadherin 18, is a member of the cadherin superfamily, which are integral membrane proteins known for their role in cell-cell adhesion, signaling, and tissue morphogenesis. CDH18 is primarily expressed in the central nervous system and has been implicated in various neurodevelopmental processes. Its role in modulating synaptic interactions and maintaining neuronal architecture has attracted attention in understanding neurological disorders such as autism spectrum disorders and schizophrenia. The study of CDH18 recombinant proteins facilitates insights into its functional mechanisms and interactions at the molecular level. These recombinant proteins serve as essential tools for elucidating the structural characteristics of CDH18, analyzing its binding affinities with other cadherins and synaptic proteins, and exploring its involvement in cellular pathways. Furthermore, investigating the potential dysregulation of CDH18 expression in neurological diseases could unveil new therapeutic targets or biomarkers. Thus, research on CDH18 recombinants is crucial for deciphering complex neuronal network behaviors and offers opportunities for developing novel strategies in treating neurodevelopmental disorders.
