Analytical Data
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Gene name
CDH18
- Application
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Alternative Names
CDH18;CDH14;Cadherin-18
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13634
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Expression Region
54-608aa
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AA Sequence
MASMTGGQQMGRGHHHHHHGNLYFQGGEFGWVWNQFFVLEEHMGPDPQYV GKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHY VLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDM GTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNM DREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQ LYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKET REGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIV GDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYN VEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTV GIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFN FFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGG IPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSS
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Molecular Weight
65 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CDH18, or Cadherin 18, is a member of the cadherin superfamily, which are integral membrane proteins known for their role in cell-cell adhesion, signaling, and tissue morphogenesis. CDH18 is primarily expressed in the central nervous system and has been implicated in various neurodevelopmental processes. Its role in modulating synaptic interactions and maintaining neuronal architecture has attracted attention in understanding neurological disorders such as autism spectrum disorders and schizophrenia. The study of CDH18 recombinant proteins facilitates insights into its functional mechanisms and interactions at the molecular level. These recombinant proteins serve as essential tools for elucidating the structural characteristics of CDH18, analyzing its binding affinities with other cadherins and synaptic proteins, and exploring its involvement in cellular pathways. Furthermore, investigating the potential dysregulation of CDH18 expression in neurological diseases could unveil new therapeutic targets or biomarkers. Thus, research on CDH18 recombinants is crucial for deciphering complex neuronal network behaviors and offers opportunities for developing novel strategies in treating neurodevelopmental disorders.











