Analytical Data
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基因名
SOX7
- Application
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别名
SOX7；Transcription factor SOX-7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BT81
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表达区间
1-388aa
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氨基酸序列
MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMN AFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAER LRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRS GSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYG LPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSP LHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHL GQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMA LSGHVPVSQVTPTGPTETSLISVLADATATYYNSYSVS
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分子量
69 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SOX7 (SRY-related HMG-box gene 7) is a member of the SOX family of transcription factors, which play crucial roles in various developmental processes and cellular functions. Initially identified for its involvement in gonadal development, SOX7 has garnered attention for its broader regulatory functions in both embryogenesis and adult tissue homeostasis. Research has indicated that SOX7 is implicated in several important biological processes, including cell differentiation, angiogenesis, and the maintenance of pluripotency in stem cells. Furthermore, aberrant expression of SOX7 has been linked to various diseases, including cancer, where it may function as a tumor suppressor. The study of SOX7 at the protein level, particularly through the production of recombinant SOX7 proteins, is crucial for understanding its structural and functional characteristics. Recombinant SOX7 proteins allow for detailed biochemical studies, including interaction assays, structural analysis, and functional assays that can elucidate the pathways and mechanisms through which SOX7 exerts its effects. Additionally, understanding the post-translational modifications and protein interactions involving SOX7 is essential for unveiling its roles in pathophysiology. Overall, the investigation of SOX7 through recombinant protein studies not only contributes to our knowledge of its fundamental biology but also holds potential for therapeutic insights in diseases where SOX7 is deregulated.
