Analytical Data
-
基因名
AFP
- Application
-
别名
CAM25547; RING finger Protein 95; RNF95; TRI26_HUMAN; TRIM26
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q12899
-
表达区间
1-609aa
-
氨基酸序列
MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKITECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNTGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLISKTRAALGV
-
分子量
95.1 KDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Alpha-fetoprotein (AFP) is a glycoprotein that plays a critical role during fetal development, primarily in the regulation of cell growth and differentiation. Its levels are typically elevated in fetal serum, but they also have significant implications in adult pathophysiology, notably in liver diseases such as hepatocellular carcinoma (HCC) and as a biomarker for certain germ cell tumors. Over the years, extensive research has focused on the potential of AFP as a therapeutic target and diagnostic marker. The recombinant forms of AFP, known as recombinant AFP proteins, are increasingly being studied for their applications in immunotherapy and targeted drug delivery, leveraging their unique properties to enhance the effectiveness of cancer treatments. Scientists are investigating the mechanisms of AFP's interaction with various cellular pathways, aiming to develop innovative strategies for cancer detection and treatment. The research into AFP recombination technology promises not only to improve disease management but also to provide insights into the biological functions of AFP in adult tissues, thereby broadening our understanding of its role in tumor biology and prenatal health. Furthermore, the recombinant proteins offer opportunities for the development of vaccines and novel therapeutic agents, driving forward the field of personalized medicine and improving patient outcomes in oncological settings. With ongoing advancements in genetic engineering and protein synthesis, the study of AFP as a recombinant protein continues to hold significant promise for both clinical and therapeutic applications.
