Analytical Data
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Gene name
SRA1
- Application
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Alternative Names
SRA1;Steroid receptor RNA activator 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HD15
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Expression Region
90-236aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSVGSGPAS GVEPTSFPVE SEAVMEDVLR PLEQALEDCR GHTRKQVCDD ISRRLALLQE QWAGGKLSIP VKKRMALLVQ ELSSHRWDAA DDIHRSLMVD HVTEVSQWMV GVKRLIAEKR SLFSEEAANE EKSAATAEKN HTIPGFQQAS
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Molecular Weight
19 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SRA1 (Steroid Receptor RNA Activator 1) is a novel protein with significant implications in gene regulation, particularly in the context of steroid receptor signaling. Research into SRA1 has gained traction due to its role as a coactivator for various nuclear hormone receptors, influencing the transcription of target genes involved in crucial physiological processes such as metabolism, development, and immune response. Its unique characteristic of being a long non-coding RNA suggests that SRA1 might function through diverse mechanisms, including RNA-protein interactions and chromatin remodeling. The exploration of SRA1's functions extends into its potential involvement in pathological conditions, including cancer, where dysregulation of steroid receptor signaling is often observed. Investigations into SRA1's structure and functional domains are necessary to fully elucidate its role in cellular processes and its interactions with other molecular players in steroid hormone signaling pathways. As the understanding of SRA1 evolves, it could pave the way for new therapeutic strategies targeting diseases linked to hormone receptor dysregulation. Overall, the study of SRA1 represents a burgeoning field that bridges molecular biology and medical research, highlighting the complexities of non-coding RNA molecules in gene expression regulation.
