Analytical Data
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基因名
SPSB2
- Application
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别名
SPSB2;GRCC9;SSB2;SPRY domain-containing SOCS box Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99619
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表达区间
1-263aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSHMGQTALAGGSSSTPTPQALYPDLSCP EGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGGLYFERRPVAQSTD GARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGS NSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEG TLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHS LLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ
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分子量
31 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SPSB2 (Sprouty-related EVH1 domain-containing protein 2) is a member of the SPSB family of proteins, which are involved in various cellular processes, including signaling pathways, cell differentiation, and the regulation of the immune response. Research into SPSB2 has gained attention due to its potential role in cancer biology, where it may influence tumor growth and metastasis by modulating key signaling pathways. Studies have shown that SPSB2 can interact with specific proteins involved in the MAPK and PI3K/Akt pathways, thereby impacting cellular proliferation and survival. Additionally, SPSB2 is implicated in the negative regulation of immune responses, making it a potential target for therapeutic interventions in autoimmune diseases and cancer. The recombinant proteins of SPSB2 are utilized in various research settings to explore its biochemical characteristics, interaction with other cellular molecules, and functional effects, providing insights into its role in health and disease. Overall, understanding the biology of SPSB2 and developing recombinant forms of the protein can lead to new therapeutic strategies in oncology and immunology, highlighting the importance of this protein in current biomedical research.
