Analytical Data
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基因名
PRR5
- Application
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别名
PRR5；PROTOR1；Proline-rich Protein 5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P85299
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表达区间
1-388aa
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氨基酸序列
MRTLRRLKFM SSPSLSDLGK REPAAAADER GTQQRRACAN ATWNSIHNGV IAVFQRKGLP DQELFSLNEG VRQLLKTELG SFFTEYLQNQ LLTKGMVILR DKIRFYEGQK LLDSLAETWD FFFSDVLPML QAIFYPVQGK EPSVRQLALL HFRNAITLSV KLEDALARAH ARVPPAIVQM LLVLQGVHES RGVTEDYLRL ETLVQKVVSP YLGTYGLHSS EGPFTHSCIL EKRLLRRSRS GDVLAKNPVV RSKSYNTPLL NPVQEHEAEG AAAGGTSIRR HSVSEMTSCP EPQGFSDPPG QGPTGTFRSS PAPHSGPCPS RLYPTTQPPE QGLDPTRSSL PRSSPENLVD QILESVDSDS EGIFIDFGRG RGSGMSDLEG SGGRQSVV
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分子量
42.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRR5 (proline-rich protein 5) is a member of the proline-rich protein family, which plays a crucial role in various biological processes, including cell signaling, growth, and differentiation. Recent studies have highlighted its involvement in cellular stress responses and its potential contributions to cancer progression and metastasis. Research has shown that PRR5 interacts with several signaling pathways, notably those related to the mammalian target of rapamycin (mTOR), which regulates cellular metabolism and growth. Given its unique structural features, such as multiple proline-rich domains, PRR5 is believed to mediate protein-protein interactions that are pivotal for cellular signaling networks. The recombinant expression of PRR5 allows for detailed functional analyses, enabling researchers to dissect its molecular mechanisms and explore its potential as a therapeutic target. The characterization of PRR5 through recombinant protein technology can facilitate the development of specific inhibitors or modulators that may be beneficial in treating diseases associated with aberrant signaling pathways, particularly in cancers. Thus, understanding PRR5's structure-function relationship through recombinant protein studies is essential for unveiling its biological roles and therapeutic potentials.
