Analytical Data
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Gene name
SPIN1
- Application
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Alternative Names
SPIN1;OCR;SPIN;Spindlin-1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y657
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Expression Region
1-262aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMKTPFGK TPGQRSRADA GHAGVSANMM KKRTSHKKHR SSVGPSKPVS QPRRNIVGCR IQHGWKEGNG PVTQWKGTVL DQVPVNPSLY LIKYDGFDCV YGLELNKDER VSALEVLPDR VATSRISDAH LADTMIGKAV EHMFETEDGS KDEWRGMVLA RAPVMNTWFY ITYEKDPVLY MYQLLDDYKE GDLRIMPDSN DSPPAEREPG EVVDSLVGKQ VEYAKEDGSK RTGMVIHQVE AKPSVYFIKF DDDFHIYVYD LVKTS
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Molecular Weight
32 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SPIN1 (SPIN1 protein) is an important regulatory protein involved in various cellular processes, including the maintenance of genomic stability and the regulation of gene expression. Research on SPIN1 has gained momentum due to its potential implications in cancer biology and developmental disorders. SPIN1 is known to function as a transcriptional regulator by interacting with multiple proteins and influencing their activity. Its role in the DNA damage response and repair mechanisms has made it a target of interest in understanding tumorigenesis, particularly in cancers where SPIN1 expression is upregulated or mutated. Additionally, studies have shown that SPIN1 may play a role in the differentiation of stem cells and neuronal development, further highlighting its significance in developmental biology. The recombinant production of SPIN1 protein allows for in-depth biochemical characterization and functional studies, providing insights into its molecular mechanisms and potential as a therapeutic target. By elucidating the pathways regulated by SPIN1, researchers aim to uncover novel strategies for cancer treatment and regenerative medicine. Consequently, the ongoing investigation into SPIN1 and its recombinant protein has significant implications for both basic research and clinical applications, fostering a deeper understanding of its role in health and disease.
