Analytical Data
-
Gene name
ADCK5
- Application
-
Alternative Names
ADCK5; Uncharacterized aarF domain-containing Protein kinase 5
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q3MIX3
-
Expression Region
1-580aa
-
AA Sequence
MWRPVQLCHFHSALLHSRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYLEVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLKFEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET
-
Molecular Weight
65.8 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADCK5 (Adoption of Coenzyme Q Biosynthesis 5) is a gene that encodes a member of the atypical kinase family and plays a crucial role in the biosynthesis of coenzyme Q, an essential component for mitochondrial electron transport and energy production. Mutations in the ADCK5 gene have been linked to a rare form of autosomal recessive ataxia, which can lead to a range of neurological disorders and mitochondrial dysfunction. Recent research has focused on the characterization of ADCK5 recombinant proteins to better understand their structure, function, and role in metabolic pathways. The generation of recombinant ADCK5 allows for the investigation of its enzymatic activity, interaction with other proteins, and the effects of specific mutations on its function. By examining the consequences of ADCK5 deficiency, scientists aim to elucidate the underlying mechanisms of related diseases and potentially develop targeted therapeutic strategies. The study of ADCK5 recombinant proteins also serves as a platform for exploring the broader implications of coenzyme Q deficiency in various pathologies, including neurodegenerative diseases and metabolic syndromes. Overall, the investigation of ADCK5 recombinant proteins is essential for advancing our understanding of mitochondrial biology and the development of novel treatments for diseases associated with mitochondrial dysfunction.
