Analytical Data
-
基因名
ADCK5
- Application
-
别名
ADCK5; Uncharacterized aarF domain-containing Protein kinase 5
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q3MIX3
-
表达区间
1-580aa
-
氨基酸序列
MWRPVQLCHFHSALLHSRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYLEVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLKFEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET
-
分子量
65.8 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADCK5 (Adoption of Coenzyme Q Biosynthesis 5) is a gene that encodes a member of the atypical kinase family and plays a crucial role in the biosynthesis of coenzyme Q, an essential component for mitochondrial electron transport and energy production. Mutations in the ADCK5 gene have been linked to a rare form of autosomal recessive ataxia, which can lead to a range of neurological disorders and mitochondrial dysfunction. Recent research has focused on the characterization of ADCK5 recombinant proteins to better understand their structure, function, and role in metabolic pathways. The generation of recombinant ADCK5 allows for the investigation of its enzymatic activity, interaction with other proteins, and the effects of specific mutations on its function. By examining the consequences of ADCK5 deficiency, scientists aim to elucidate the underlying mechanisms of related diseases and potentially develop targeted therapeutic strategies. The study of ADCK5 recombinant proteins also serves as a platform for exploring the broader implications of coenzyme Q deficiency in various pathologies, including neurodegenerative diseases and metabolic syndromes. Overall, the investigation of ADCK5 recombinant proteins is essential for advancing our understanding of mitochondrial biology and the development of novel treatments for diseases associated with mitochondrial dysfunction.
