Analytical Data
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Gene name
ADAM30
- Application
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Alternative Names
ADA30_HUMAN; ADAM 30; ADAM metallopeptidase domain 30
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UKF2
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Expression Region
1-790aa
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AA Sequence
MRSVQIFLSQCRLLLLLVPTMLLKSLGEDVIFHPEGEFDSYEVTIPEKLSFRGEVQGVVSPVSYLLQLKGKKHVLHLWPKRLLLPRHLRVFSFTEHGELLEDHPYIPKDCNYMGSVKESLDSKATISTCMGGLRGVFNIDAKHYQIEPLKASPSFEHVVYLLKKEQFGNQVCGLSDDEIEWQMAPYENKARLRDFPGSYKHPKYLELILLFDQSRYRFVNNNLSQVIHDAILLTGIMDTYFQDVRMRIHLKALEVWTDFNKIRVGYPELAEVLGRFVIYKKSVLNARLSSDWAHLYLQRKYNDALAWSFGKVCSLEYAGSVSTLLDTNILAPATWSAHELGHAVGMSHDEQYCQCRGRLNCIMGSGRTGFSNCSYISFFKHISSGATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEECQKDRCCQSNCKLQPGANCSIGLCCHDCRFRPSGYVCRQEGNECDLAEYCDGNSSSCPNDVYKQDGTPCKYEGRCFRKGCRSRYMQCQSIFGPDAMEAPSECYDAVNLIGDQFGNCEITGIRNFKKCESANSICGRLQCINVETIPDLPEHTTIISTHLQAENLMCWGTGYHLSMKPMGIPDLGMINDGTSCGEGRVCFKKNCVNSSVLQFDCLPEKCNTRGVCNNRKNCHCMYGWAPPFCEEVGYGGSIDSGPPGLLRGAIPSSIWVVSIIMFRLILLILSVVFVFFRQVIGNHLKPKQEKMPLSKAKTEQEESKTKTVQEESKTKTGQEESEAKTGQEESKAKTGQEESKANIESERPKAKSVKKQKK
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Molecular Weight
113.3 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADAM30, a member of the ADAM (A Disintegrin and Metalloproteinase) family, is a type I transmembrane protein characterized by its metalloproteinase and disintegrin-like domains. Recent research has highlighted its potential roles in various biological processes, including cell adhesion, migration, and proteolytic cleavage of extracellular matrix components. These functions are particularly relevant in the context of cancer progression, where ADAM30 has been implicated in tumor cell invasion and metastasis. The study of recombinant ADAM30 protein has gained importance as it allows for the detailed investigation of its structure-function relationships and interactions with other proteins. Recombinant techniques enable the production of ADAM30 in vitro, facilitating its purification and characterization for functional assays and structural studies. Understanding the biochemical pathways involving ADAM30 could unveil novel therapeutic targets for cancer treatment and other diseases. Additionally, investigating the regulatory mechanisms governing ADAM30 expression and activity may offer insights into its role in pathophysiological conditions. Current research is focused on elucidating the specific substrates of ADAM30, its regulatory mechanisms, and its potential as a biomarker or therapeutic target in oncology. Through these investigations, scientists aim to delineate its precise contributions to cellular processes and its implications in disease states, specifically in oncological settings.
